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Authors
Hill, William
Lim, Emilia L.
Weeden, Clare E.
Lee, Claudia https://orcid.org/0000-0003-1715-2265
Augustine, Marcellus
Chen, Kezhong
Kuan, Feng-Che
Marongiu, Fabio
Evans, Edward J. Jr https://orcid.org/0000-0001-8120-3755
Moore, David A. https://orcid.org/0000-0002-6296-1312
Rodrigues, Felipe S.
Pich, Oriol https://orcid.org/0000-0002-1956-1882
Bakker, Bjorn https://orcid.org/0000-0003-3095-7287
Cha, Hongui
Myers, Renelle
van Maldegem, Febe
Boumelha, Jesse
Veeriah, Selvaraju
Rowan, Andrew
Naceur-Lombardelli, Cristina
Karasaki, Takahiro https://orcid.org/0000-0001-6863-2360
Sivakumar, Monica
De, Swapnanil
Caswell, Deborah R.
Nagano, Ai https://orcid.org/0000-0002-2354-660X
Black, James R. M.
Martínez-Ruiz, Carlos https://orcid.org/0000-0002-4817-0565
Ryu, Min Hyung
Huff, Ryan D. https://orcid.org/0000-0002-6038-8217
Li, Shijia
Favé, Marie-Julie
Magness, Alastair
Suárez-Bonnet, Alejandro https://orcid.org/0000-0003-0296-5896
Priestnall, Simon L. https://orcid.org/0000-0002-6027-1879
Lüchtenborg, Margreet
Lavelle, Katrina
Pethick, Joanna
Hardy, Steven
McRonald, Fiona E. https://orcid.org/0000-0001-7226-9461
Lin, Meng-Hung https://orcid.org/0000-0002-8594-3360
Troccoli, Clara I.
Ghosh, Moumita
Miller, York E.
Merrick, Daniel T.
Keith, Robert L.
Al Bakir, Maise https://orcid.org/0000-0002-0846-8332
Bailey, Chris
Hill, Mark S. https://orcid.org/0000-0003-0718-8934
Saal, Lao H.
Chen, Yilun
George, Anthony M. https://orcid.org/0000-0001-5680-8664
Abbosh, Christopher https://orcid.org/0000-0002-8983-1382
Kanu, Nnennaya
Lee, Se-Hoon https://orcid.org/0000-0002-9219-3350
McGranahan, Nicholas https://orcid.org/0000-0001-9537-4045
Berg, Christine D.
Sasieni, Peter https://orcid.org/0000-0003-1509-8744
Houlston, Richard https://orcid.org/0000-0002-5268-0242
Turnbull, Clare
Lam, Stephen
Awadalla, Philip https://orcid.org/0000-0001-9946-6393
Grönroos, Eva https://orcid.org/0000-0001-8303-5409
Downward, Julian https://orcid.org/0000-0002-2331-4729
Jacks, Tyler https://orcid.org/0000-0001-5785-8911
Carlsten, Christopher
Malanchi, Ilaria https://orcid.org/0000-0003-4867-3311
Hackshaw, Allan https://orcid.org/0000-0002-5570-5070
Litchfield, Kevin https://orcid.org/0000-0002-3725-0914
,
Lester, Jason F.
Bajaj, Amrita
Nakas, Apostolos
Sodha-Ramdeen, Azmina
Ang, Keng
Tufail, Mohamad
Chowdhry, Mohammed Fiyaz
Scotland, Molly
Boyles, Rebecca
Rathinam, Sridhar
Wilson, Claire
Marrone, Domenic
Dulloo, Sean
Fennell, Dean A.
Matharu, Gurdeep
Shaw, Jacqui A.
Riley, Joan
Primrose, Lindsay
Boleti, Ekaterini
Cheyne, Heather
Khalil, Mohammed
Richardson, Shirley
Cruickshank, Tracey
Price, Gillian
Kerr, Keith M.
Benafif, Sarah
Gilbert, Kayleigh
Naidu, Babu
Patel, Akshay J.
Osman, Aya
Lacson, Christer
Langman, Gerald
Shackleford, Helen
Djearaman, Madava
Kadiri, Salma
Middleton, Gary
Leek, Angela
Hodgkinson, Jack Davies
Totten, Nicola
Montero, Angeles
Smith, Elaine
Fontaine, Eustace
Granato, Felice
Doran, Helen
Novasio, Juliette
Rammohan, Kendadai
Joseph, Leena
Bishop, Paul
Shah, Rajesh
Moss, Stuart
Joshi, Vijay
Crosbie, Philip
Gomes, Fabio
Brown, Kate
Carter, Mathew
Chaturvedi, Anshuman
Priest, Lynsey
Oliveira, Pedro
Lindsay, Colin R.
Blackhall, Fiona H.
Krebs, Matthew G.
Summers, Yvonne
Clipson, Alexandra
Tugwood, Jonathan
Kerr, Alastair
Rothwell, Dominic G.
Kilgour, Elaine
Dive, Caroline
Aerts, Hugo J. W. L.
Schwarz, Roland F.
Kaufmann, Tom L.
Wilson, Gareth A.
Rosenthal, Rachel
Van Loo, Peter
Birkbak, Nicolai J.
Szallasi, Zoltan
Kisistok, Judit
Sokac, Mateo
Salgado, Roberto
Diossy, Miklos
Demeulemeester, Jonas
Bunkum, Abigail
Stewart, Aengus
Frankell, Alexander M.
Karamani, Angeliki
Toncheva, Antonia
Huebner, Ariana
Chain, Benny
Campbell, Brittany B.
Castignani, Carla
Puttick, Clare
Richard, Corentin
Hiley, Crispin T.
Pearce, David R.
Karagianni, Despoina
Biswas, Dhruva
Levi, Dina
Hoxha, Elena
Cadieux, Elizabeth Larose
Colliver, Emma
Nye, Emma
Gálvez-Cancino, Felip
Athanasopoulou, Foteini
Gimeno-Valiente, Francisco
Kassiotis, George
Stavrou, Georgia
Mastrokalos, Gerasimos
Zhai, Haoran
Lowe, Helen L.
Matos, Ignacio Garcia
Goldman, Jacki
Reading, James L.
Herrero, Javier
Rane, Jayant K.
Nicod, Jerome
Lam, Jie Min
Hartley, John A.
Peggs, Karl S.
Enfield, Katey S. S.
Selvaraju, Kayalvizhi
Thol, Kerstin
Ng, Kevin W.
Dijkstra, Krijn
Grigoriadis, Kristiana
Thakkar, Krupa
Ensell, Leah
Shah, Mansi
Duran, Marcos Vasquez
Litovchenko, Maria
Sunderland, Mariana Werner
Dietzen, Michelle
Leung, Michelle
Escudero, Mickael
Angelova, Mihaela
Tanić, Miljana
Chervova, Olga
Lucas, Olivia
Al-Sawaf, Othman
Prymas, Paulina
Hobson, Philip
Pawlik, Piotr
Stone, Richard Kevin
Bentham, Robert
Hynds, Robert E.
Vendramin, Roberto
Saghafinia, Sadegh
López, Saioa
Gamble, Samuel
Ung, Seng Kuong Anakin
Quezada, Sergio A.
Vanloo, Sharon
Zaccaria, Simone
Hessey, Sonya
Ward, Sophia
Boeing, Stefan
Beck, Stephan
Bola, Supreet Kaur
Denner, Tamara
Marafioti, Teresa
Mourikis, Thanos P.
Watkins, Thomas B. K.
Spanswick, Victoria
Barbè, Vittorio
Lu, Wei-Ting
Liu, Wing Kin
Wu, Yin
Naito, Yutaka
Ramsden, Zoe
Veiga, Catarina
Royle, Gary
Collins-Fekete, Charles-Antoine
Fraioli, Francesco
Ashford, Paul
Clark, Tristan
Forster, Martin D.
Lee, Siow Ming
Borg, Elaine
Falzon, Mary
Papadatos-Pastos, Dionysis
Wilson, James
Ahmad, Tanya
Procter, Alexander James
Ahmed, Asia
Taylor, Magali N.
Nair, Arjun
Lawrence, David
Patrini, Davide
Navani, Neal
Thakrar, Ricky M.
Janes, Sam M.
Hoogenboom, Emilie Martinoni
Monk, Fleur
Holding, James W.
Choudhary, Junaid
Bhakhri, Kunal
Scarci, Marco
Hayward, Martin
Panagiotopoulos, Nikolaos
Gorman, Pat
Khiroya, Reena
Stephens, Robert C. M.
Wong, Yien Ning Sophia
Bandula, Steve
Sharp, Abigail
Smith, Sean
Gower, Nicole
Dhanda, Harjot Kaur
Chan, Kitty
Pilotti, Camilla
Leslie, Rachel
Grapa, Anca
Zhang, Hanyun
AbdulJabbar, Khalid
Pan, Xiaoxi
Yuan, Yinyin
Chuter, David
MacKenzie, Mairead
Chee, Serena
Alzetani, Aiman
Cave, Judith
Scarlett, Lydia
Richards, Jennifer
Ingram, Papawadee
Austin, Silvia
Lim, Eric
De Sousa, Paulo
Jordan, Simon
Rice, Alexandra
Raubenheimer, Hilgardt
Bhayani, Harshil
Ambrose, Lyn
Devaraj, Anand
Chavan, Hema
Begum, Sofina
Buderi, Silviu I.
Kaniu, Daniel
Malima, Mpho
Booth, Sarah
Nicholson, Andrew G.
Fernandes, Nadia
Shah, Pratibha
Proli, Chiara
Hewish, Madeleine
Danson, Sarah
Shackcloth, Michael J.
Robinson, Lily
Russell, Peter
Blyth, Kevin G.
Dick, Craig
Le Quesne, John
Kirk, Alan
Asif, Mo
Bilancia, Rocco
Kostoulas, Nikos
Thomas, Mathew
DeGregori, James https://orcid.org/0000-0002-1287-1976
Jamal-Hanjani, Mariam https://orcid.org/0000-0003-1212-1259
Swanton, Charles https://orcid.org/0000-0002-4299-3018
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Article History
Received: 17 June 2022
Accepted: 21 February 2023
First Online: 5 April 2023
Competing interests
: M.A.B. has consulted for Achilles Therapeutics. L.H.S., Y.C. and A.M.G. have ownership interest in SAGA Diagnostics. S.V. is a co-inventor to a patent to detecting molecules in a sample (US patent 10578620). D.A.M. reports speaker fees from AstraZeneca, Eli Lilly and Takeda, consultancy fees from AstraZeneca, Thermo Fisher, Takeda, Amgen, Janssen, MIM Software, Bristol-Myers Squibb and Eli Lilly, and has received educational support from Takeda and Amgen. C.A. has received speaking honoraria or expenses from Novartis, Roche, AstraZeneca and Bristol-Myers Squibb and reports employment at AstraZeneca. C.A. is an inventor on a European patent application relating to assay technology to detect tumour recurrence (PCT/GB2017/053289). The patent has been licensed to commercial entities and under their terms of employment, C.A is due a revenue share of any revenue generated from such licence(s). C.A. declares a patent application (PCT/US2017/028013) for methods to detect lung cancer. C.A. is a named inventor on a patent application to determine methods and systems for tumour monitoring (PCT/EP2022/077987). T.J. is a member of the Board of Directors of Amgen and Thermo Fisher Scientific, and a co-Founder of Dragonfly Therapeutics and T2 Biosystems. T.J. serves on the Scientific Advisory Board (SAB) of Dragonfly Therapeutics, SQZ Biotech and Skyhawk Therapeutics. T.J. is also President of Break Through Cancer. K. Litchfield has a patent on indel burden and CPI response pending and speaker fees from Roche tissue diagnostics, research funding from CRUK TDL–Ono–LifeArc alliance, Genesis Therapeutics, and consulting roles with Ellipses Pharma, Monopteros and Kynos Therapeutics. N.M. has received consultancy fees and has stock options in Achilles Therapeutics. N.M. holds European patents relating to targeting neoantigens (PCT/EP2016/ 059401), identifying patient response to immune checkpoint blockade (PCT/EP2016/071471), determining HLA LOH (PCT/GB2018/052004), and predicting survival rates of patients with cancer (PCT/GB2020/050221). C.T. has received honoraria for educational activities and advisory boards from AstraZeneca and Roche (all proceeds donated to registered charity 11511580). C.D.B. has consultantships with GRAIL, LLC, NHS Galleri Trial, IDMC, Mercy BioAnalytics, Lucid DX and Medial EarlySign. J. Downward has acted as a consultant for AstraZeneca, Jubilant, Theras, Roche and Vividion and has funded research agreements with Bristol-Myers Squibb, Revolution Medicines and AstraZeneca. A.H. has received fees for being a member of Independent Data Monitoring Committees for Roche-sponsored clinical trials, and academic projects co-ordinated by Roche. M.J.-H. is a CRUK Career Establishment Awardee and has received funding from CRUK, NIH National Cancer Institute, IASLC International Lung Cancer Foundation, Lung Cancer Research Foundation, Rosetrees Trust, UKI NETs, NIHR, NIHR UCLH Biomedical Research Centre. M.J.-H. has consulted for, and is a member of, the Achilles Therapeutics Scientific Advisory Board and Steering Committee, has received speaker honoraria from Pfizer, Astex Pharmaceuticals, Oslo Cancer Cluster, Bristol Myers Squibb, and is co-inventor on a European patent application relating to methods to detect lung cancer PCT/US2017/028013).M.G., Y.E.M., R.L.K. and D.T.M. acknowledge grant support from Bristol-Myers Squibb. C.S. acknowledges grant support from AstraZeneca, Boehringer-Ingelheim, Bristol-Myers Squibb, Pfizer, Roche-Ventana, Invitae (previously Archer Dx Inc–collaboration in minimal residual disease sequencing technologies), and Ono Pharmaceutical. C.S. is an AstraZeneca Advisory Board member and Chief Investigator for the AZ MeRmaiD 1 and 2 clinical trials and is also Co-Chief Investigator of the NHS Galleri trial funded by GRAIL and a paid member of GRAIL’s SAB. He receives consultant fees from Achilles Therapeutics (also SAB member), Bicycle Therapeutics (also a SAB member), Genentech, Medicxi, Roche Innovation Centre–Shanghai, Metabomed (until July 2022), and the Sarah Cannon Research Institute. He had stock options in Apogen Biotechnologies and GRAIL until June 2021, and currently has stock options in Epic Bioscience, Bicycle Therapeutics, and has stock options and is co-founder of Achilles Therapeutics. C.S. is an inventor on a European patent application relating to assay technology to detect tumour recurrence (PCT/GB2017/053289), the patent has been licensed to commercial entities, and under his terms of employment, C.S. is due a revenue share of any revenue generated from such licence(s). C.S. holds patents relating to targeting neoantigens (PCT/EP2016/059401), identifying patient response to immune checkpoint blockade (PCT/EP2016/071471), determining HLA LOH (PCT/GB2018/052004), predicting survival rates of patients with cancer (PCT/GB2020/050221), identifying patients who respond to cancer treatment (PCT/GB2018/051912), a US patent relating to detecting tumour mutations (PCT/US2017/28013), methods for lung cancer detection (US20190106751A1) and both a European and US patent related to identifying insertion/deletion mutation targets (PCT/GB2018/051892) and is co-inventor to a patent application to determine methods and systems for tumour monitoring (PCT/EP2022/077987). C.S has received honoraria from Amgen, AstraZeneca, Pfizer, Novartis, GlaxoSmithKline, MSD, Bristol Myers Squibb, Illumina, and Roche-Ventana.
