Müller, Miryam https://orcid.org/0000-0002-0751-1407
May, Stephanie https://orcid.org/0000-0003-0095-7403
Hall, Holly https://orcid.org/0000-0003-2779-2565
Kendall, Timothy J. https://orcid.org/0000-0002-4174-2786
McGarry, Lynn https://orcid.org/0000-0002-7055-2615
Blukacz, Lauriane https://orcid.org/0000-0002-1144-4024
Nuciforo, Sandro https://orcid.org/0000-0002-1863-1869
Georgakopoulou, Anastasia https://orcid.org/0000-0001-9328-7466
Jamieson, Thomas
Phinichkusolchit, Narisa
Dhayade, Sandeep
Suzuki, Toshiyasu https://orcid.org/0000-0002-2711-0360
Huguet-Pradell, Júlia https://orcid.org/0000-0003-1489-356X
Powley, Ian R. https://orcid.org/0009-0009-6079-6673
Officer-Jones, Leah https://orcid.org/0000-0002-3690-2386
Pennie, Rachel L.
Esteban-Fabró, Roger https://orcid.org/0000-0002-8173-3323
Gris-Oliver, Albert https://orcid.org/0000-0003-1802-9541
Pinyol, Roser https://orcid.org/0000-0002-0288-6314
Skalka, George L.
Leslie, Jack https://orcid.org/0000-0001-6443-2396
Hoare, Matthew https://orcid.org/0000-0001-5990-9604
Sprangers, Joep
Malviya, Gaurav
Mackintosh, Agata
Johnson, Emma https://orcid.org/0009-0005-4362-3974
McCain, Misti https://orcid.org/0000-0002-1967-0421
Halpin, John https://orcid.org/0000-0003-3313-5190
Kiourtis, Christos https://orcid.org/0000-0002-6682-5668
Nixon, Colin https://orcid.org/0000-0002-8085-2160
Clark, Graeme
Clark, William
Shaw, Robin https://orcid.org/0000-0001-5503-5233
Hedley, Ann
Drake, Thomas M.
Tan, Ee Hong
Neilson, Matt
Murphy, Daniel J. https://orcid.org/0000-0002-5538-5468
Lewis, David Y. https://orcid.org/0000-0001-9329-1326
Reeves, Helen L. https://orcid.org/0000-0003-0359-9795
Le Quesne, John https://orcid.org/0000-0003-3552-7446
Mann, Derek A. https://orcid.org/0000-0003-0950-243X
Carlin, Leo M. https://orcid.org/0000-0001-7172-5234
Blyth, Karen https://orcid.org/0000-0002-9304-439X
Llovet, Josep M.
Heim, Markus H. https://orcid.org/0000-0002-7523-4894
Sansom, Owen J. https://orcid.org/0000-0001-9540-3010
Miller, Crispin J. https://orcid.org/0000-0003-4341-1283
Bird, Thomas G. https://orcid.org/0000-0002-6120-1581
Article History
Received: 9 May 2022
Accepted: 2 January 2025
First Online: 19 February 2025
Competing interests
: Material for the lenvatinib day 15 and day 30 timepoint experiments (Fig. ) was provided by Eisai. AZD2171 was provided by AstraZeneca. D.A.M. is a director, shareholder and employee of FibroFind. L.M.C. has consulted for Ono Pharmaceuticals UK on unrelated work. J.M.L. is receiving research support from Eisai Inc and Bayer Pharmaceuticals; is consulting and performing sponsored lectures for Eisai Inc., Merck, Roche, Genentech, AstraZeneca, Bayer Pharmaceuticals, AbbVie, Sanofi, Moderna, Glycotest and Exelixis; and participates in the Data Safety Monitoring Board for Bristol Myers Squibb. The other authors declare no competing interests.