Guo, Yinliang https://orcid.org/0009-0004-8118-5357
Li, Yiheng https://orcid.org/0009-0004-3944-4781
Chen, Sihan https://orcid.org/0009-0009-3272-8040
Wu, Yige
Poll, Oscar
Ren, Zhouyang
Liu, Zhonglin
Vlkolinsky, Roman
Bajo, Michal
Prier, Christopher K. https://orcid.org/0000-0003-0902-1636
Xiao, Kai-Jiong https://orcid.org/0000-0001-5613-2035
Cravatt, Benjamin F. https://orcid.org/0000-0001-5330-3492
Roberto, Marisa https://orcid.org/0000-0003-0729-3961
Baran, Phil S. https://orcid.org/0000-0001-9193-9053
Article History
Received: 5 January 2025
Accepted: 19 August 2025
First Online: 26 August 2025
Competing interests
: C.K.P. is a former employee of Merck Sharp & Dohme LLC, a subsidiary of Merck & Co., Inc., and he is co-inventor of the patent governing hydroxylase enzyme sequences reported in the article (PCT/US2020/061237). Codexis, Inc. is the assignee of the patent governing the engineered enzyme sequence reported in the article (PCT/US2020/061237), and the enzyme is now commercially available as FrbA-Rd10bb. The other authors declare no competing interests.