Burger, Domenic https://orcid.org/0000-0002-4181-2588
Kashyrina, Marianna
van den Heuvel, Lukas https://orcid.org/0000-0001-9168-8450
de La Seiglière, Hortense https://orcid.org/0009-0007-2828-5780
Lewis, Amanda J.
De Nuccio, Francesco
Mohammed, Inayathulla
Verchère, Jérémy
Feuillie, Cécile
Berbon, Mélanie
Arotcarena, Marie-Laure
Retailleau, Aude https://orcid.org/0000-0001-6367-1889
Bezard, Erwan https://orcid.org/0000-0002-0410-4638
Canron, Marie-Hélène
Meissner, Wassilios G. https://orcid.org/0000-0003-2172-7527
Loquet, Antoine https://orcid.org/0000-0001-7176-7813
Bousset, Luc https://orcid.org/0000-0002-0433-4337
Poujol, Christel
Nilsson, K. Peter R.
Laferrière, Florent https://orcid.org/0000-0002-0753-5505
Baron, Thierry https://orcid.org/0000-0001-5396-7707
Lofrumento, Dario Domenico
De Giorgi, Francesca
Stahlberg, Henning https://orcid.org/0000-0002-1185-4592
Ichas, François https://orcid.org/0000-0001-8184-5248
Article History
Received: 19 May 2024
Accepted: 1 October 2025
First Online: 5 November 2025
Change Date: 10 March 2026
Change Type: Update
Change Details: In the version of this article originally published, ref. 31 listed an incorrect article and has now been amended to cite Boyer et al. (<i>Nat. Struct. Mol. Biol.</i>
Change Details: https://doi.org/10.1038/s41594-019-0322-y
Change Details: (2019)). In the last paragraph of the “MSA-like neuropathology seeded by 1B” section, callouts to panels in Extended Data Fig. 3 in the second, fourth and fifth sentences were incorrect. The reference and callouts are now amended in the HTML and PDF versions of the article.
Competing interests
: D.B. is an employee of F. Hoffmann–La Roche. The presented work was conducted before his employment and had no influence on the design, analysis, interpretation or reporting of the results of this study. E.B. is a director and shareholder and of Motac Neuroscience. The other authors declare no competing interests.