Meisel, Joshua D. https://orcid.org/0000-0002-6944-5177
Joshi, Pallavi R.
Spelbring, Amy N.
Wang, Hong
Wellner, Sandra M.
Wiesenthal, Presli P. https://orcid.org/0000-0002-7757-6652
Miranda, Maria https://orcid.org/0000-0002-0817-553X
McCoy, Jason G. https://orcid.org/0009-0008-3094-7154
Barondeau, David P.
Ruvkun, Gary https://orcid.org/0000-0002-7473-8484
Mootha, Vamsi K. https://orcid.org/0000-0001-9924-642X
Article History
Received: 3 October 2024
Accepted: 28 October 2025
First Online: 10 December 2025
Competing interests
: V.K.M. is listed as an inventor on patents filed by MGH on therapeutic uses of hypoxia. J.D.M., G.R. and V.K.M. are listed as inventors on a patent filed by MGH on technology reported in this paper; J.D.M., G.R. and V.K.M. own equity in and are paid advisors to Falcon Bio, a company focusing on this technology. V.K.M. is a paid advisor to 5am Ventures. Other authors do not have any competing interests.