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Authors
Wang, Daisong https://orcid.org/0009-0005-9194-8132
Lim, Sangho
van de Wetering, Willine J. https://orcid.org/0000-0003-0311-978X
Lopez-Iglesias, Carmen
Okura, Yuu https://orcid.org/0000-0002-6949-8105
Teranishi-Ikawa, Yuri
Mizoroki, Akihiko
Spoelstra, Willem Kasper https://orcid.org/0000-0002-7940-0829
Dayton, Talya
van Son, Gijs J. F. https://orcid.org/0000-0003-0572-3243
Pronk, Apollo
Smakman, Niels
Gonera-de Jong, Gieneke B. C.
Withoff, Sebo
Jonkers, Iris H. https://orcid.org/0000-0003-2304-7939
van Zon, Jeroen S. https://orcid.org/0000-0002-6021-2924
Tans, Sander J. https://orcid.org/0000-0002-7131-2568
Peters, Peter J. https://orcid.org/0000-0002-2964-5684
van Es, Johan H.
Clevers, Hans https://orcid.org/0000-0002-3077-5582
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Article History
Received: 3 September 2024
Accepted: 29 October 2025
First Online: 10 December 2025
Competing interests
: H.C. was the head of Pharma Research and Early Development at Roche, Basel and holds several patents related to organoids technology. His full disclosure can be found at . Y.O., Y.T.-I. and A.M. are employees of Chugai Pharmaceutical and inventors on patents (WO 2022/059766) related to DONQ52, of which all rights have been assigned to the company.
