Friedrich, Mirco J.
Pham, Julie https://orcid.org/0009-0000-5678-5220
Tian, Jiakun https://orcid.org/0000-0002-1238-780X
Chen, Hongyu https://orcid.org/0000-0002-9496-8586
Huang, Jiahao https://orcid.org/0000-0002-6349-9799
Kehl, Niklas
Liu, Sophia https://orcid.org/0000-0003-3614-9731
Lash, Blake https://orcid.org/0000-0003-2445-7948
Chen, Fei https://orcid.org/0000-0003-2308-3649
Wang, Xiao https://orcid.org/0000-0002-3090-9894
Macrae, Rhiannon K. https://orcid.org/0000-0002-7850-9056
Zhang, Feng https://orcid.org/0000-0003-0178-7995
Article History
Received: 4 October 2024
Accepted: 5 November 2025
First Online: 17 December 2025
Competing interests
: M.J.F. and F.Z. are co-inventors on US provisional patent application no. 63/530,465 filed by the Broad Institute and MIT relating to this work. F.Z. is a scientific advisor and cofounder of Beam Therapeutics, Pairwise Plants, Arbor Biotechnologies, Aera Therapeutics and Moonwalk Biosciences; and is a scientific advisor for Octant. M.J.F. reports speaker honoraria and consulting fees from Pfizer, Roche, Kerna Ventures and Moonwalk Biosciences. X.W. is a scientific cofounder and consultant of Stellaromics and Convergence Bio. All other authors declare no competing interests.