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Authors
Siraj, Layla
Castro, Rodrigo I. https://orcid.org/0000-0002-9833-4169
Dewey, Hannah B. https://orcid.org/0000-0002-3009-0452
Kales, Susan
Butts, John C. https://orcid.org/0000-0001-9456-4509
Nguyen, Thanh Thanh L. https://orcid.org/0000-0002-2281-6540
Kanai, Masahiro https://orcid.org/0000-0001-5165-4408
Berenzy, Daniel https://orcid.org/0000-0001-8695-8903
Mouri, Kousuke https://orcid.org/0000-0003-1712-6833
Wang, Qingbo S.
Fiziev, Petko P.
Tsuo, Kristin
McCaw, Zachary R. https://orcid.org/0000-0002-2006-9828
Gosai, Sager J. https://orcid.org/0000-0003-4494-7362
Aguet, François
Cui, Ran https://orcid.org/0000-0002-3236-4082
Kassam, Irfahan
McRae, Jeremy https://orcid.org/0000-0003-3411-9248
Vockley, Christopher M.
Lareau, Caleb A. https://orcid.org/0000-0003-4179-4807
Abramov, Sergey https://orcid.org/0000-0002-3334-5334
Boystov, Alexandr https://orcid.org/0000-0002-2712-8368
Vierstra, Jeff https://orcid.org/0000-0001-6406-8563
Okada, Yukinori https://orcid.org/0000-0002-0311-8472
Gusev, Alexander https://orcid.org/0000-0002-7980-4620
Jones, Thouis R. https://orcid.org/0000-0001-6584-9660
Lander, Eric S. https://orcid.org/0000-0003-2662-4631
Sabeti, Pardis C. https://orcid.org/0000-0002-9843-1890
Finucane, Hilary K. https://orcid.org/0000-0003-3864-9828
Reilly, Steven K. https://orcid.org/0000-0003-3140-1483
Ulirsch, Jacob C. https://orcid.org/0000-0002-7947-0827
Tewhey, Ryan https://orcid.org/0000-0002-4607-8001
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Article History
Received: 31 July 2024
Accepted: 9 January 2026
First Online: 25 February 2026
Competing interests
: P.C.S. is a co-founder of, and former consultant to, Sherlock Biosciences and a former board member of the Danaher Corporation, and is a co-founder of, and equity holder of, Lyra Labs. P.C.S. and R.T. hold patents related to the application of MPRA. J.C.U., P.P.F., I.K. and J.M. are employees of Illumina. F.A. was an employee of Illumina when this work was performed and is currently an employee and equity holder of Predicta Biosciences. Q.S.W. is an employee of Calico Life Sciences LLC. C.M.V. is an employee of Eli Lilly and Company. Z.R.M. was an employee of insitro when this work was done. The remaining authors declare no competing interests.
