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Authors
Roth, Mitchell O.
Shu, Yuerong
Zhao, Yu https://orcid.org/0000-0003-0485-2780
Trasanidou, Despoina
Hoffman, Renee D.
Südfeld, Christian
Bouzetos, Eugenios
Trasanidis, Nikolaos https://orcid.org/0000-0001-9795-3059
Zawrotny, Michael https://orcid.org/0000-0003-3830-9321
Gelasco, Mary K.
Medina, Megan L.
Das, Anuska
Rai, Jay
Goswami, Hemant N.
Wang, Bing
van der Oost, John https://orcid.org/0000-0001-5024-1871
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Article History
Received: 23 January 2024
Accepted: 9 March 2026
First Online: 15 April 2026
Change Date: 23 April 2026
Change Type: Update
Change Details: In the version of this article initially published, the Gene Expression Omnibus accession GSE322563 was listed incorrectly in the Data availability section and is now amended in the HTML and PDF versions of the article.
Competing interests
: A patent application on methylation-sensitive gene editing using ThermoCas9 and its variants has been filed related to this work with the following information: Florida State University Research Foundation, INC, Wageningen University are the patent applicants under PCT/US2025/014770 (published as US2025/0250641 on 8 July 2025), with H.L., M.O.R., Y.S., Y.Z., R.D.H., J.v.d.O. and D.T. named as inventors. The application is pending. J.v.d.O. is an advisor of NTrans Technologies, Scope Biosciences and Hudson River Biotechnology. The other authors declare no competing interests.
