Layeghifard, Mehdi https://orcid.org/0000-0002-6224-3628
Díaz-Gay, Marcos https://orcid.org/0000-0003-0658-0467
Bergstrom, Erik N.
Mahendralingam, Mathepan J.
Light, Nicholas
Blay, Sasha https://orcid.org/0000-0002-5611-2330
Nash, Joshua O.
Anderson, Nathaniel D. https://orcid.org/0000-0003-4523-6327
Au, Jessica N. https://orcid.org/0000-0002-5043-2245
Davidson, Scott
Ballester, Pedro L. https://orcid.org/0000-0001-9928-2527
Wen, Timmy
Daud, Syed Kashif
Edward, Lisa-Monique https://orcid.org/0000-0002-1113-7913
Ashiqul Islam, S. M.
Khandekar, Azhar
Otlu, Burçak https://orcid.org/0000-0002-4931-7979
Brunga, Ledia
Hammad, Rawan https://orcid.org/0000-0001-6293-7497
Nassif, Shimaa
Thacker, Nirav H.
Feltham, Tara
Fuentes-Bolanos, Noemi A.
Wong-Erasmus, Marie https://orcid.org/0000-0003-0066-6606
Levine, Max F.
Miller, Katherine E. https://orcid.org/0000-0003-1054-0476
Shukla, Neerav N.
Kinnaman, Michael D.
Glodzik, Dominik https://orcid.org/0000-0001-8112-9073
Portwine, Carol
Millson, Sabrina
Zorzi, Alexandra P.
Mikhail, Mariam
Fernandez, Conrad V. https://orcid.org/0000-0002-0746-8306
Wheaton, Laura
Gundem, Gunes https://orcid.org/0000-0002-0070-9859
Kung, Andrew L.
Tabori, Uri https://orcid.org/0000-0002-5019-2683
Mayoh, Chelsea https://orcid.org/0000-0002-6398-3046
Papaemmanuil, Elli https://orcid.org/0000-0003-1709-8983
Cowley, Mark J. https://orcid.org/0000-0002-9519-5714
Malkin, David https://orcid.org/0000-0001-5752-9763
Villani, Anita
Alexandrov, Ludmil B.
Shlien, Adam https://orcid.org/0000-0002-0368-5370
Article History
Received: 3 March 2025
Accepted: 12 June 2026
First Online: 22 July 2026
Ethics
Competing interests: A.L.K. is co-founder of, and on the Scientific Advisory Board of, Isabl, has equity interest in Isabl, and is an inventor of MSK intellectual property licensed to Isabl. E.N.B. and L.B.A. declare a US provisional patent application filed with the University of California, San Diego with serial number 63/269,033. M.D.-G. and L.B.A. declare a European patent application with application number EP25305077.7. L.B.A. is a co-founder, chief scientific officer, scientific advisory member and consultant for io9 (now Acurion), and has equity and receives income. The terms of this arrangement have been reviewed and approved by the University of California, San Diego in accordance with its conflict-of-interest policies. L.B.A. is a compensated member of the scientific advisory board of Inocras. L.B.A. declares US provisional applications with serial numbers: 63/289,601; 63/269,033; 63/366,392; 63/412,835 as well as international patent application PCT/US2023/010679. L.B.A. is also an inventor of US patent 10,776,718 for source identification by non-negative matrix factorization. A.S. is co-founder of NewCode Oncology, a cancer diagnostics company, and is an inventor of intellectual property licensed to the company. The other authors declare no competing interests.