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Authors
Sakai, Holt A. https://orcid.org/0000-0002-9338-1484
Pierce, Sarah E.
Jiang, Allen Y. https://orcid.org/0000-0002-9826-5976
Cristian, Ana
An, Meirui https://orcid.org/0000-0002-4006-8670
Kim, Chae Rin
Ahmed, Nouraiz
Hemez, Colin F.
Tao, Y. Allen
Zhang, Emily https://orcid.org/0000-0002-9053-1336
Wu, Sophia J.
Liu, David R. https://orcid.org/0000-0002-9943-7557
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Funding
Funding for this research was provided by:
U.S. Department of Health & Human Services | NIH | National Institute of General Medical Sciences (R35GM118062)
U.S. Department of Health & Human Services | NIH | National Human Genome Research Institute (RM1HG009490)
Howard Hughes Medical Institute (Liu investigatorship)
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Article History
Received: 11 October 2025
Accepted: 7 April 2026
First Online: 20 May 2026
Competing interests
: H.A.S., S.E.P. and D.R.L. are inventors of a patent application filed by the Broad Institute on the motif sequences reported herein. D.R.L. is a cofounder of Beam Therapeutics, Prime Medicine, Editas Medicine, Pairwise Plants and nChroma Bio, companies that use or deliver genome-editing agents. The other authors declare no competing interests.
