Jiménez-Sánchez, Alejandro https://orcid.org/0000-0003-1879-7057
Cybulska, Paulina
Mager, Katherine LaVigne
Koplev, Simon https://orcid.org/0000-0002-8586-5614
Cast, Oliver https://orcid.org/0000-0002-5880-7726
Couturier, Dominique-Laurent https://orcid.org/0000-0001-5774-5036
Memon, Danish https://orcid.org/0000-0002-1365-0710
Selenica, Pier
Nikolovski, Ines
Mazaheri, Yousef
Bykov, Yonina
Geyer, Felipe C.
Macintyre, Geoff https://orcid.org/0000-0003-3906-467X
Gavarró, Lena Morrill https://orcid.org/0000-0002-2242-4010
Drews, Ruben M.
Gill, Michael B.
Papanastasiou, Anastasios D.
Sosa, Ramon E.
Soslow, Robert A.
Walther, Tyler
Shen, Ronglai
Chi, Dennis S.
Park, Kay J.
Hollmann, Travis
Reis-Filho, Jorge S. https://orcid.org/0000-0003-2969-3173
Markowetz, Florian https://orcid.org/0000-0002-2784-5308
Beltrao, Pedro https://orcid.org/0000-0002-2724-7703
Vargas, Hebert Alberto
Zamarin, Dmitriy
Brenton, James D. https://orcid.org/0000-0002-5738-6683
Snyder, Alexandra
Weigelt, Britta
Sala, Evis https://orcid.org/0000-0002-5518-9360
Miller, Martin L. https://orcid.org/0000-0003-3161-8690
Funding for this research was provided by:
Cancer Research UK (C14303/A17197, C14303/A17197, A22905, C14303/A17197, A19274, A15973, A19274, A19274)
Target Ovarian Cancer (Cambridge-MM18)
Brown Performance Innovation in Cancer Informatics Discovery Award
Cancer Research UK Cambridge Institute and the Mexican National Council of Science and Technology (CONACyT).
Breast Cancer Research Foundation
Kaleidoscope of Hope GrantCycle for Survival Grant
Kaleidoscope of Hope Grant
The Mark Foundation
Society of Memorial Sloan Kettering
Marsha Rivkin OrganizationTranslational and Integrative Medicine Research Fund (MSKCC), Kaleidoscope of Hope
Ovarian Cancer Research Alliance Liz Tilberis Award
University of Cambridge Harding Distinguished Postgraduate Scholars Programme
European Bioinformatics Institute
EMBL-EBI & NIHR Cambridge Biomedical Research Centre Postdoctoral (EBPOD) program.
Instituto de Salud Carlos III (ISCIII), Spanish Ministry of Science and Innovation.
Wellcome Trust
Wellcome Trust grant through the Mathematical Genomics and Medicine programme.
United States Department of Defense | United States Army | Army Medical Command | Congressionally Directed Medical Research Programs
Article History
Received: 1 October 2018
Accepted: 20 April 2020
First Online: 1 June 2020
Competing interests
: A.S. is a current employee of, and owns stock in, Merck. D.S.C. is a member of two medical advisory boards and invested in two surgical companies, none of which are related to this research. J.S.R.-F. is a paid consultant of Goldman Sachs Merchant Banking, Paige.AI and REPARE Therapeutics; a member of the scientific advisory board with paid honoraria of Paige.AI and Volition Rx; and an ad hoc member of the scientific advisory boards of Roche Tissue Diagnostics, Ventana, InVicro, Genentech, Novartis, GRAIL and Roche, outside the scope of the submitted work. D.Z. reports personal/consultancy fees from Merck, Synlogic Therapeutics, Biomed Valley Discoveries, Trieza Therapeutics, Tesaro and Agenus, outside of the scope of the submitted work. M.L.M. has received honoraria from GSK not related to this research. E.S. is a cofounder and shareholder of Cambridge AI Health and a consultant for Amazon and has received honoraria from GSK; none of these are related to this research. G.M. is founder and CTO of Pinpoint Oncology Ltd. A.J.-S. has owned and sold stocks while this work was in progress, none of which is directly related to this publication.