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Authors
Zhao, Yajie https://orcid.org/0000-0002-2747-0219
Chukanova, Maria
Kentistou, Katherine A. https://orcid.org/0000-0002-5816-664X
Fairhurst-Hunter, Zammy
Siegert, Anna Maria
Jia, Raina Y.
Dowsett, Georgina K. C.
Gardner, Eugene J. https://orcid.org/0000-0001-9671-1533
Lawler, Katherine https://orcid.org/0000-0003-4188-1804
Day, Felix R. https://orcid.org/0000-0003-3789-7651
Kaisinger, Lena R. https://orcid.org/0000-0002-0849-3191
Tung, Yi-Chun Loraine
Lam, Brian Yee Hong https://orcid.org/0000-0002-3638-9025
Chen, Hsiao-Jou Cortina https://orcid.org/0000-0001-6315-9850
Wang, Quanli
Berumen-Campos, Jaime https://orcid.org/0000-0001-6707-3317
Kuri-Morales, Pablo https://orcid.org/0000-0002-0704-9507
Tapia-Conyer, Roberto https://orcid.org/0000-0003-3814-2904
Alegre-Diaz, Jesus https://orcid.org/0000-0001-9390-3871
Barroso, Inês https://orcid.org/0000-0001-5800-4520
Emberson, Jonathan https://orcid.org/0000-0001-7792-9422
Torres, Jason M. https://orcid.org/0000-0002-7537-7035
Collins, Rory
Saleheen, Danish
Smith, Katherine R. https://orcid.org/0000-0002-0329-5938
Paul, Dirk S. https://orcid.org/0000-0002-8230-0116
Merkle, Florian https://orcid.org/0000-0002-8513-2998
Farooqi, I. Sadaf
Wareham, Nick J. https://orcid.org/0000-0003-1422-2993
Petrovski, Slavé https://orcid.org/0000-0002-1527-961X
O’Rahilly, Stephen https://orcid.org/0000-0003-2199-4449
Ong, Ken K. https://orcid.org/0000-0003-4689-7530
Yeo, Giles S. H. https://orcid.org/0000-0001-8823-3615
Perry, John R. B. https://orcid.org/0000-0001-6483-3771
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Funding
Funding for this research was provided by:
RCUK | Medical Research Council (MC_UU_00006/1, MC_UU_00006/2, MC_UU_00006/1, MC_UU_00006/2, (MR/S026193/1, MC_UU_00006/1, MC_UU_00006/2, MR/S026193/1, MC_UU_00006/1, MC_UU_00006/2, MC_UU_00006/1, MC_UU_00006/2, MC_UU_00006/1, MC_UU_00006/2, MC_UU_00006/1, MC_UU_00006/2, MC_UU_00014/1, MC_UU_00014/1, MC_UU_00006/1, MC_UU_00006/2, MC_UU_00006/1, MC_UU_00006/2, MC_UU_00014/1)
RCUK | Biotechnology and Biological Sciences Research Council (Doctoral Training Programme)
Wellcome Trust (211221/Z/18/Z, 207462/Z/17/Z)
Chan Zuckerberg Initiative
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Article History
Received: 5 June 2023
Accepted: 21 February 2024
First Online: 4 April 2024
Competing interests
: Z.F.-H., Q.W., K.R.S., D.S.P. and S.P. are employees and/or stockholders of AstraZeneca. J.R.B.P. and E.J.G. are employees and shareholders of Insmed. J.R.B.P. receives research funding from GSK. Y.Z. is a UK University worker at GSK. I.S.F. has consulted for a number of companies developing weight loss drugs, including Eli Lilly, Novo Nordisk and Rhythm Pharmaceuticals. G.S.H.Y. receives grant funding from Novo Nordisk and consults for both Novo Nordisk and Eli Lilly. S.O.R. has undertaken remunerated consultancy work for Pfizer, Third Rock Ventures, AstraZeneca, NorthSea Therapeutics and Courage Therapeutics. The other authors declare no competing interests.
