Alberge, Jean-Baptiste https://orcid.org/0000-0002-4218-7294
Dutta, Ankit K.
Poletti, Andrea https://orcid.org/0000-0002-0753-1248
Coorens, Tim H. H. https://orcid.org/0000-0002-5826-3554
Lightbody, Elizabeth D.
Toenges, Rosa
Loinaz, Xavi https://orcid.org/0009-0002-4999-2605
Wallin, Sofia
Dunford, Andrew
Priebe, Oliver
Dagan, Johnathan
Boehner, Cody J.
Horowitz, Erica
Su, Nang K.
Barr, Hadley
Hevenor, Laura
Towle, Katherine
Beesam, Rashmika
Beckwith, Jenna B.
Perry, Jacqueline
Cordas dos Santos, David M. https://orcid.org/0000-0002-9198-8338
Bertamini, Luca
Greipp, Patricia T. https://orcid.org/0000-0002-5536-9011
Kübler, Kirsten https://orcid.org/0000-0002-0342-5579
Arndt, Peter F. https://orcid.org/0000-0003-1762-9836
Terragna, Carolina
Zamagni, Elena
Boyle, Eileen M.
Yong, Kwee
Morgan, Gareth https://orcid.org/0000-0002-4271-6360
Walker, Brian A. https://orcid.org/0000-0002-8615-6254
Dimopoulos, Meletios Athanasios https://orcid.org/0000-0001-8990-3254
Kastritis, Efstathios
Hess, Julian https://orcid.org/0000-0003-1387-4009
Sklavenitis-Pistofidis, Romanos
Stewart, Chip
Getz, Gad https://orcid.org/0000-0002-0936-0753
Ghobrial, Irene M. https://orcid.org/0000-0001-7361-3092
Funding for this research was provided by:
EIF | Stand Up To Cancer (SU2C-AACR-DT-28-18)
EIF | Stand Up To Cancer (SU2C-AACR-DT-28-18)
Multiple Myeloma Research Foundation (-)
Dr. Miriam and Sheldon G. Adelson Medical Research Foundation (-)
International Myeloma Society Career Development Award
Dana-Farber Cancer Institute
Deutsche Forschungsgemeinschaft
Article History
Received: 4 July 2024
Accepted: 15 April 2025
First Online: 21 May 2025
Competing interests
: J.-B.A., A.K.D., G.G. and I.M.G. are inventors on patent applications for MinimuMM-seq and for the MM-like score. A.K.D. and E.D.L. have consulted for and received honoraria from Menarini Silicon Biosystems. G.G. receives research funds from IBM, Pharmacyclics/Abbvie, Bayer, Genentech, Calico, Ultima Genomics, Inocras, Google, Kite and Novartis, and is also an inventor on patent applications filed by the Broad Institute related to MSMuTect, MSMutSig, POLYSOLVER, SignatureAnalyzer-GPU, MSEye, MinimuMM-seq, and DLBclass. He is a founder, consultant and holds private equity in Scorpion Therapeutics; he is also a founder of and holds privately held equity in Predicta Biosciences. He was also a consultant to Merck. I.M.G. has consulted for Bristol-Myers Squibb, AstraZeneca, Amgen, Curio Science, Sanofi, Janssen, Pfizer, Menarini Silicone Biosystems, Aptitude Health, GlaxoSmithKline, AbbVie, Adaptive Biotechnologies, Window Therapeutics and Regeneron. She has received honoraria or speaker fees from Vor Biopharma, Janssen, MJH Life Sciences, Novartis, Takeda, Amgen, Regeneron, Curio Science, Standard Biotools and Physicians’ Education Resource. She is a founder and executive board member of and holds private equity in Predicta Biosciences. Her spouse is the chief medical officer of and holds private equity in Disc Medicine. R.S.P. is a founder, consultant and holds equity in Predicta Biosciences. E.Z. has received honoraria and served in advisory roles for Janssen, Bristol-Myers Squibb, Sanofi, Amgen, GlaxoSmithKline, Pfizer, Oncopeptides and Menarini–Stemline. The other authors declare no competing interests.