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Authors
Gimeno-Valiente, Francisco
Castignani, Carla
Larose Cadieux, Elizabeth https://orcid.org/0000-0002-9320-8040
Mensah, Nana E.
Liu, Xiaohong
Chen, Kezhong
Chervova, Olga
Karasaki, Takahiro https://orcid.org/0000-0001-6863-2360
Weeden, Clare E.
Richard, Corentin
Lai, Siqi
Martínez-Ruiz, Carlos https://orcid.org/0000-0002-4817-0565
Lim, Emilia L.
Frankell, Alexander M. https://orcid.org/0000-0002-0341-7878
Watkins, Thomas B. K.
Stavrou, Georgia https://orcid.org/0000-0002-8427-5233
Usaite, Ieva
Lu, Wei-Ting https://orcid.org/0000-0002-1405-4806
Marinelli, Daniele https://orcid.org/0000-0002-6002-363X
Saghafinia, Sadegh
Wilson, Gareth A.
Dhami, Pawan https://orcid.org/0000-0002-5408-1833
Vaikkinen, Heli
Steif, Jonathan
Veeriah, Selvaraju
Hynds, Robert E. https://orcid.org/0000-0002-2170-8791
Hirst, Martin
Hiley, Crispin
Feber, Andrew
Deniz, Özgen https://orcid.org/0000-0001-7268-1923
Jamal-Hanjani, Mariam https://orcid.org/0000-0003-1212-1259
McGranahan, Nicholas https://orcid.org/0000-0001-9537-4045
,
Bentham, Robert
Jones, Thomas P.
Black, James R. M.
Dietzen, Michelle
Litovchenko, Maria
Thol, Kerstin
Bunkum, Abigail
Hessey, Sonya
Liu, Wing Kin
Birkbak, Nicolai J.
Huebner, Ariana
Puttick, Clare
Moore, David A.
Biswas, Dhruva
Grigoriadis, Kristiana
Bakir, Maise Al
Lucas, Olivia
Vendramin, Roberto
Ward, Sophia
Harries, Sian
Zaccaria, Simone
Zaidi, Rija
Patruno, Lucrezia
Karagianni, Despoina
Quezada, Sergio A.
Bola, Supreet Kaur
Forster, Martin D.
Lee, Siow Ming
Naceur-Lombardelli, Cristina
Thakkar, Krupa
Sivakumar, Monica
Vanloo, Sharon
Toncheva, Antonia
Prymas, Paulina
Mussa, Bushra
Magala, Michalina
Keene, Elizabeth
Leung, Michelle M.
Kittel, Jeanette
Haase, Kerstin
Koh, Kexin
Scott, Rachel
Bailey, Chris
Pich, Oriol
Rosenthal, Rachel
Rowan, Andrew
Lee, Claudia
Colliver, Emma
Enfield, Katey S. S.
Angelova, Mihaela
Murphy, Cian
Zagorulya, Maria
Rane, Jayant K.
Zhang, Zhihui
Benafif, Sarah
Papadatos-Pastos, Dionysis
Wilson, James
Ahmad, Tanya
Marafioti, Teresa
Borg, Elaine
Falzon, Mary
Khiroya, Reena
Wong, Yien Ning Sophia
Hoogenboom, Emilie Martinoni
Monk, Fleur
Holding, James W.
Choudhary, Junaid
Bhakhri, Kunal
Gorman, Pat
Stephens, Robert C. M.
Pisciella, Maria Chiara
Bandula, Steve
Nicod, Jerome
Dwornik, Angela
Karamani, Angeliki
Chain, Benny
Pearce, David R.
Mastrokalos, Gerasimos-Theodoros
Lowe, Helen L.
Reading, James L.
Hartley, John A.
Selvaraju, Kayalvizhi
Ensell, Leah
Shah, Mansi
Pawlik, Piotr
Gamble, Samuel
Ung, Seng Kuong Anakin
Spanswick, Victoria
Wu, Yin
Lester, Jason F.
Dulloo, Sean
Fennell, Dean A.
Bajaj, Amrita
Nakas, Apostolos
Sodha-Ramdeen, Azmina
Tufail, Mohamad
Scotland, Molly
Boyles, Rebecca
Rathinam, Sridhar
Wilson, Claire
Matharu, Gurdeep
Shaw, Jacqui A.
Boleti, Ekaterini
Cheyne, Heather
Khalil, Mohammed
Richardson, Shirley
Cruickshank, Tracey
Price, Gillian
Kerr, Keith M.
French, Jack
Gilbert, Kayleigh
Naidu, Babu
Patel, Akshay J.
Middleton, Gary
Osman, Aya
Sangha, Mandeesh
Langman, Gerald
Shackleford, Helen
Djearaman, Madava
Leek, Angela
Hodgkinson, Jack Davies
Totton, Nicola
Crosbie, Philip
Fontaine, Eustace
Granato, Felice
Novasio, Juliette
Rammohan, Kendadai
Joseph, Leena
Bishop, Paul
Joshi, Vijay
Waplington, Sara
Atkin, Adam
Brown, Katherine D.
Carter, Mathew
Chaturvedi, Anshuman
Oliveira, Pedro
Lindsay, Colin R.
Blackhall, Fiona H.
Summers, Yvonne
Tugwood, Jonathan
Dive, Caroline
Krebs, Matthew G.
Paiva-Correia, Antonio
Aerts, Hugo J. W. L.
Schwarz, Roland F.
Kaufmann, Tom L.
Szallasi, Zoltan
Diossy, Miklos
Salgado, Roberto
Kassiotis, George
Noorani, Imran
Grönroos, Eva
Goldman, Jacki
Escudero, Mickael
Hobson, Philip
Boeing, Stefan
Denner, Tamara
Barbè, Vittorio
Hill, William
Naito, Yutaka
Sahai, Erik
Ramsden, Zoe
Nye, Emma
Stone, Richard Kevin
Peggs, Karl S.
Veiga, Catarina
Royle, Gary
Collins-Fekete, Charles-Antoine
Fraioli, Francesco
Ashford, Paul
Nair, Arjun
Procter, Alexander James
Ahmed, Asia
Taylor, Magali N.
Lawrence, David
Patrini, Davide
Navani, Neal
Thakrar, Ricky M.
Janes, Sam M.
Kaplar, Zoltan
Hackshaw, Allan
Pilotti, Camilla
Leslie, Rachel
Hacker, Anne-Marie
Smith, Sean
Walker, Aoife
Grapa, Anca
Zhang, Hanyun
AbdulJabbar, Khalid
Pan, Xiaoxi
Yuan, Yinyin
Chuter, David
MacKenzie, Mairead
Chee, Serena
Georg, Patricia
Alzetani, Aiman
Cave, Judith
Lim, Eric
Nicholson, Andrew G.
De Sousa, Paulo
Jordan, Simon
Rice, Alexandra
Raubenheimer, Hilgardt
Bhayani, Harshil
Ambrose, Lyn
Devaraj, Anand
Chavan, Hema
Begum, Sofina
Buderi, Silviu I.
Kaniu, Daniel
Malima, Mpho
Booth, Sarah
Fernandes, Nadia
Shah, Pratibha
Proli, Chiara
Hewish, Madeleine
Danson, Sarah
Shackcloth, Michael J.
Robinson, Lily
Russell, Peter
Blyth, Kevin G.
Kidd, Andrew
Dick, Craig
Le Quesne, John
Kirk, Alan
Asif, Mo
Bilancia, Rocco
Kostoulas, Nikos
Whiteley, Jennifer
Thomas, Mathew
Beck, Stephan https://orcid.org/0000-0001-5290-2151
Demeulemeester, Jonas https://orcid.org/0000-0002-2660-2478
Tanić, Miljana https://orcid.org/0000-0003-3102-776X
Swanton, Charles https://orcid.org/0000-0002-4299-3018
Van Loo, Peter https://orcid.org/0000-0003-0292-1949
Kanu, Nnennaya https://orcid.org/0000-0001-7232-1952
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Article History
Received: 1 October 2024
Accepted: 21 July 2025
First Online: 10 September 2025
Competing interests
: E.L.C. is currently employed by and holds shares in Achilles Therapeutics. N.K. acknowledges grant support from AstraZeneca. C.S. acknowledges grants from AstraZeneca, Boehringer Ingelheim, Bristol Myers Squibb, Pfizer, Roche-Ventana, Invitae (previously Archer Dx, a collaboration in minimal residual disease sequencing technologies), Ono Pharmaceutical and Personalis. He is Chief Investigator for the AZ MeRmaiD 1 and 2 clinical trials and is the Steering Committee Chair. He is also Co-Chief Investigator of the NHS Galleri trial funded by GRAIL and a paid member of GRAIL’s Scientific Advisory Board (SAB). He receives consultant fees from Achilles Therapeutics (he is also a SAB member), Bicycle Therapeutics (he is also a SAB member), Genentech, Medicxi, the China Innovation Centre of Roche, formerly the Roche Innovation Centre, Metabomed (until July 2022) and the Sarah Cannon Research Institute. C.S. has received honoraria from Amgen, AstraZeneca, Bristol Myers Squibb, GlaxoSmithKline, Illumina, MSD, Novartis, Pfizer and Roche-Ventana. C.S. has previously held stock options in Apogen Biotechnologies and GRAIL, and currently has stock options in Epic Bioscience and Bicycle Therapeutics, and has stock options and is co-founder of Achilles Therapeutics. C.S. declares a patent application (no. PCT/US2017/028013) for methods to lung cancer; for targeting neoantigens (no. PCT/EP2016/059401); for identifying patent response to immune checkpoint blockade (no. PCT/EP2016/071471); for determining HLA LOH (no. PCT/GB2018/052004); for predicting the survival rates of patients with cancer (no. PCT/GB2020/050221); for identifying patients who respond to cancer treatment (no. PCT/GB2018/051912); and for methods for lung cancer detection (no. US20190106751A1). C.S. is an inventor on a European patent application (no. PCT/GB2017/053289) relating to assay technology to detect tumor recurrence. This patent has been licensed to a commercial entity; under their terms of employment, C.S. is due a revenue share of any revenue generated from such license(s). J.D. has consulted for AvH. M.J.-H. has received funding from CRUK, the National Institutes of Health National Cancer Institute, the International Association for the Study of Lung Cancer, the Lung Cancer Research Foundation, the Rosetrees Trust, the UK and Ireland Neuroendocrine Tumour Society and the NIHR. M.J.-H. has consulted for, and is a member of, the Achilles Therapeutics SAB and Steering Committee, has received speaker honoraria from Pfizer, Astex Pharmaceuticals, the Oslo Cancer Cluster and Bristol Myers Squibb, and is listed as a co-inventor on a European patent application relating to methods to detect lung cancer (no. PCT/US2017/028013). This patent has been licensed to commercial entities and, under the terms of employment, M.J.-H. is due a share of any revenue generated from such license(s). A.M.F. is a co-inventor on a patent application to determine methods and systems for tumor monitoring (no. PCT/EP2022/077987). S.V. is a co-inventor on a patent of methods for detecting molecules in a sample (no. 10578620). The other authors declare no competing interests.
