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Authors
Zhao, Yajie https://orcid.org/0000-0002-2747-0219
Lockhart, Sam https://orcid.org/0000-0003-2092-4350
Liu, Jimmy https://orcid.org/0000-0002-8379-5480
Li, Xihao https://orcid.org/0000-0001-8151-0106
Cortes, Adrian https://orcid.org/0000-0002-3490-007X
Hua, Xing
Gardner, Eugene J. https://orcid.org/0000-0001-9671-1533
Kentistou, Katherine A. https://orcid.org/0000-0002-5816-664X
Cañadas-Garre, Marisa
Fabian, Laurie https://orcid.org/0009-0007-3145-5357
Ho, Karen
Timpson, Nicholas https://orcid.org/0000-0002-7141-9189
Lo, Yancy https://orcid.org/0000-0003-2843-4882
Davitte, Jonathan
Savage, David B. https://orcid.org/0000-0002-7857-7032
Buser-Doepner, Carolyn
Ong, Ken K.
Zhang, Haoyu https://orcid.org/0000-0001-6423-0444
Scott, Robert https://orcid.org/0000-0003-3634-3016
O’Rahilly, Stephen https://orcid.org/0000-0003-2199-4449
Perry, John R. B. https://orcid.org/0000-0001-6483-3771
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Article History
Received: 27 May 2024
Accepted: 9 September 2025
First Online: 10 October 2025
Competing interests
: J.L., A.C., Y.L., J.D., C.B.-D. and R.S. are employees and stockholders of GSK. J.R.B.P. and E.J.G. are employees and shareholders of Insmed. J.R.B.P. receives research funding from GSK. Y.Z. was a UK University worker at GSK during this work. S.O.ʼR. has undertaken remunerated consultancy work for Pfizer, Third Rock Ventures, AstraZeneca, NorthSea Therapeutics and Courage Therapeutics and is a scientific founder of Marea Therapeutics. S.L. performs paid consultancy for Eolas Medical. The other authors declare no competing interests.
