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Authors
Kaplan, Eleanor G.
Steger, Ryan J.
Shah, Spencer T. https://orcid.org/0009-0002-9082-3969
Drepanos, Laura M. https://orcid.org/0009-0001-5807-1923
Griffith, Audrey L. https://orcid.org/0000-0001-5552-2939
Reint, Ganna
Doench, John G. https://orcid.org/0000-0002-3707-9889
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Article History
Received: 23 November 2024
Accepted: 10 September 2025
First Online: 14 October 2025
Competing interests
: J.G.D. consults for Microsoft Research, BioNTech, PhenomicAI, Servier and Pfizer. J.G.D. consults for and has equity in Tango Therapeutics. J.G.D. serves as a paid scientific advisor to the Laboratory for Genomics Research, funded in part by GSK, and the Innovative Genomics Institute, funded in part by Apple Tree Partners. J.G.D. receives funding support from the Functional Genomics Consortium: AbbVie, Bristol Myers Squibb, Janssen and Merck. J.G.D.’s interests are reviewed and managed by the Broad Institute in accordance with its conflict of interest policies. A patent application related to this work has been filed. The other authors declare no competing interests.
