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Authors
Small, Aeron M.
Yang, Ta-Yu https://orcid.org/0000-0002-5379-5340
Itoh, Shinsuke https://orcid.org/0000-0001-9567-8188
Thériault, Sébastien https://orcid.org/0000-0003-1893-8307
Dufresne, Line https://orcid.org/0000-0001-6923-8517
Kurosawa, Ryo
Komuro, Issei
Matsuda, Koichi https://orcid.org/0000-0001-7292-2686
Vy, Ha My T.
Farber-Eger, Eric H. https://orcid.org/0000-0003-0281-3796
Shaffer, Lauren Lee
Boulier, Kristin M.
Corey, Kristin M.
Ramaker, Megan E.
Laporte, Fabien https://orcid.org/0000-0003-2509-3293
Schott, Jean-Jacques https://orcid.org/0000-0002-9578-9475
Le Scouarnec, Solena https://orcid.org/0000-0003-3444-2125
Singh, Sasha A.
Sonawane, Abhijeet R.
Smith, Harry A.
Rafaels, Nicholas
,
Ghouse, Jonas https://orcid.org/0000-0002-9634-5964
Raja, Anna A.
Ostrowski, Sisse R. https://orcid.org/0000-0001-5288-3851
Sørensen, Erik https://orcid.org/0000-0002-5002-9077
Mikkelsen, Christina https://orcid.org/0000-0002-2945-6197
Pedersen, Ole B. https://orcid.org/0000-0003-2312-5976
Erikstrup, Christian https://orcid.org/0000-0001-6551-6647
Ullum, Henrik
,
Sveinbjornsson, Gardar
Gudbjartsson, Daniel F.
Abner, Erik https://orcid.org/0000-0002-6529-3161
,
Lee, Jiwoo https://orcid.org/0000-0003-0555-585X
Ganna, Andrea https://orcid.org/0000-0002-8147-240X
Nowak-Göttl, Ulrike
Finer, Sarah https://orcid.org/0000-0002-2684-4653
,
van Heel, David A.
Schumacher, Johannes https://orcid.org/0000-0001-9217-6457
Maj, Carlo https://orcid.org/0000-0002-9559-1725
Al-Kassou, Baravan
Nickenig, Georg
Trenkwalder, Teresa
Dreβen, Martina https://orcid.org/0000-0003-2200-6254
Krane, Markus
Nöthen, Markus M.
Moksnes, Marta R. https://orcid.org/0000-0002-2690-5153
Brumpton, Ben M. https://orcid.org/0000-0002-3058-1059
Knight, Stacey https://orcid.org/0000-0003-0092-7327
Knowlton, Kirk U.
Nadauld, Lincoln
Debiec, Radek
Musameh, Muntaser D.
Braund, Peter S. https://orcid.org/0000-0001-8540-5709
Nelson, Christopher P.
Czuba, Tomasz https://orcid.org/0009-0001-0232-0425
Melander, Olle
Selvaraj, Margaret Sunitha https://orcid.org/0000-0002-2751-9254
Koyama, Satoshi https://orcid.org/0000-0002-9286-0360
Bhukar, Rohan
Ruan, Yunfeng
Ljungberg, Johan https://orcid.org/0000-0002-3002-4877
Damrauer, Scott M. https://orcid.org/0000-0001-8009-1632
Levin, Michael G. https://orcid.org/0000-0002-9937-9932
Franke, Andre https://orcid.org/0000-0003-1530-5811
Berger, Klaus
Ruff, Christian T.
Melloni, Giorgio E. M. https://orcid.org/0000-0001-6371-1334
Kamanu, Frederick K.
Ito, Kaoru https://orcid.org/0000-0003-1843-773X
Do, Ron https://orcid.org/0000-0002-3144-3627
Loos, Ruth J. F. https://orcid.org/0000-0002-8532-5087
Schunkert, Heribert https://orcid.org/0000-0001-6428-3001
Wells, Quinn S.
Shah, Svati H.
Le Tourneau, Thierry https://orcid.org/0000-0002-0110-9054
Messika-Zeitoun, David
Gignoux, Christopher https://orcid.org/0000-0001-9728-6567
Bundgaard, Henning https://orcid.org/0000-0002-0563-7049
Larsson, Susanna C.
Michaëlsson, Karl
Holm, Hilma
Helgadottir, Anna
Esko, Tonu
van Heel, David A. https://orcid.org/0000-0002-0637-2265
Mathieu, Patrick https://orcid.org/0000-0002-3805-2004
Samani, Nilesh J.
Smith, J. Gustav https://orcid.org/0000-0001-6285-9935
Söderberg, Stefan https://orcid.org/0000-0001-9225-1306
Rader, Daniel J.
Marston, Nicholas A. https://orcid.org/0000-0001-6164-4617
Sabatine, Marc S.
Pasaniuc, Bogdan
Cho, Kelly
Wilson, Peter W. F. https://orcid.org/0000-0002-5653-7056
O’Donnell, Christopher J. https://orcid.org/0000-0002-2667-8624
Stefansson, Kari https://orcid.org/0000-0003-1676-864X
Bossé, Yohan https://orcid.org/0000-0002-3067-3711
Aikawa, Elena
Engert, James C. https://orcid.org/0000-0001-8411-4790
Peloso, Gina M. https://orcid.org/0000-0002-5355-8636
Natarajan, Pradeep https://orcid.org/0000-0001-8402-7435
Thanassoulis, George https://orcid.org/0000-0002-9930-7189
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Funding
Funding for this research was provided by:
Gouvernement du Canada | Canadian Institutes of Health Research
Fonds de Recherche du Québec - Santé
Heart and Stroke Foundation of Canada
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Article History
Received: 6 September 2024
Accepted: 17 October 2025
First Online: 19 December 2025
Competing interests
: Authors affiliated with deCODE genetics/Amgen are employed by the company (G.S., D.F.G., A.F., K.S., A.H. and H.H.). M.K. is a physician proctor and a member of the medical advisory board for JOMDD, a physician proctor for Peter Duschek, a medical consultant for EVOTEC and Moderna and has received speakers’ honoraria from Medtronic and Terumo. S.M.D. has research support from Renalytix and Novo Nordisk. R.J.F.L. is a consultant for Eli Lilly and Novo Nordisk. S.S. receives speaker’s honoraria and is on the scientific board for Johnson & Johnson. C.J.O. is employed by Novartis Pharmaceuticals. P.N. reports research grants from Allelica, Amgen, Apple, Boston Scientific, Genentech/Roche and Novartis, personal fees from Allelica, Apple, AstraZeneca, Blackstone Life Sciences, Creative Education Concepts, CRISPR Therapeutics, Eli Lilly, Esperion Therapeutics, Foresite Capital, Foresite Labs, Genentech/Roche, GV, HeartFlow, Magnet Biomedicine, Merck, Novartis, TenSixteen Bio, and Tourmaline Bio, equity in Bolt, Candela, Mercury, MyOme, Parameter Health, Preciseli, and TenSixteen Bio, and spousal employment at Vertex Pharmaceuticals, all unrelated to the present work. G.T. has received consulting fees from Ionis Pharmaceuticals and has participated in advisory boards for Amgen, Sanofi, Novartis, HLS Therapeutics and Silence, all unrelated to the current work. The other authors declare no competing interests.
