Calvo Fernández, Ester https://orcid.org/0000-0001-6307-8452
Tomassoni, Lorenzo
Zhang, Xu
Wang, Junqiang
Obradovic, Aleksandar
Laise, Pasquale https://orcid.org/0000-0003-1469-4704
Griffin, Aaron T.
Vlahos, Lukas
Minns, Hanna E.
Morales, Diana V. https://orcid.org/0009-0005-8590-861X
Simmons, Christian
Gallitto, Matthew
Wei, Hong-Jian
Martins, Timothy J. https://orcid.org/0000-0002-2133-7281
Becker, Pamela S. https://orcid.org/0000-0001-6235-9463
Crawford, John R.
Tzaridis, Theophilos
Wechsler-Reya, Robert J.
Garvin, James https://orcid.org/0000-0003-4709-1088
Gartrell, Robyn D.
Szalontay, Luca
Zacharoulis, Stergios
Wu, Cheng-Chia
Zhang, Zhiguo https://orcid.org/0000-0002-9451-2685
Califano, Andrea https://orcid.org/0000-0003-4742-3679
Pavisic, Jovana https://orcid.org/0000-0002-6968-600X
Article History
Received: 16 September 2024
Accepted: 18 February 2026
First Online: 22 April 2026
Competing interests
: A.C. is a founder, equity holder and consultant of DarwinHealth, a company that has licensed some of the algorithms used in this paper from Columbia University. Columbia University is also an equity holder in DarwinHealth. P.L. and L.T. work at DarwinHealth. S.Z. was the senior director of pediatric oncology at Bristol Myers Squibb during this study, but no longer holds that position. P.S.B. is a consultant at Accordant Health Services and has received research funding from GPCR Therapeutics. The remaining authors declare no competing interests.