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Article History
Received: 27 July 2024
Accepted: 28 April 2026
First Online: 9 June 2026
Competing interests
: This work was supported by funding from Calico Life Sciences. R.T.M. and K.B.Y. receive research funding from Calico Life Sciences. N.B. has received a research grant from Servier Laboratories. R.T.M. has received speaking or consulting fees from Bristol Myers Squibb, Gilead Sciences, Kumquat Biosciences, Immunai Therapeutics and BioNTech, and has equity ownership in OncoRev. Calico Life Sciences and the Broad Institute participated in data interpretation and in the review and approval of the paper. The remaining authors declare no competing interests.