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Authors
Shiba, Satoshi
Yachida, Shinichi https://orcid.org/0000-0001-5507-4566
Mizutani, Sayaka https://orcid.org/0000-0003-4168-6195
Totoki, Yasushi https://orcid.org/0000-0003-1876-6859
Nakamura, Hiromi
Hama, Natsuko
Miyoshi, Norikatsu https://orcid.org/0000-0003-1113-8884
Arai, Yasuhito https://orcid.org/0000-0001-6306-9409
Saito-Adachi, Mihoko https://orcid.org/0000-0001-9213-0184
Kimura, Hirokazu
Hayashi, Yoshito
Takamaru, Hiroyuki
Tanaka, Koji
Hayashi, Rie
Rokutan, Hirofumi https://orcid.org/0000-0003-4172-4892
Ikuta, Shoko
Kanemitsu, Yukihide
Doki, Yuichiro
Eguchi, Hidetoshi
Hattori, Satoshi
Saito, Yutaka
Yamada, Takuji https://orcid.org/0000-0002-9622-1849
Shibata, Tatsuhiro https://orcid.org/0000-0002-0477-210X
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Article History
Received: 12 December 2025
Accepted: 23 June 2026
First Online: 10 August 2026
Ethics
Competing interests: T.Y. is a co-founder of Metagen, Metagen Therapeutics and digzyme and holds equity interests in these companies. These entities had no role in the design of the study; the collection, analysis or interpretation of the data; or the writing of the paper and decision to publish. In accordance with its conflict-of-interest policies, the Institute of Science Tokyo manages the terms of these arrangements. The other authors declare no competing interests.
