Posternak, Ganna
Tang, Xiaojing
Maisonneuve, Pierre http://orcid.org/0000-0001-8292-5741
Jin, Ting http://orcid.org/0000-0001-7252-0361
Lavoie, Hugo
Daou, Salima
Orlicky, Stephen
Goullet de Rugy, Theo
Caldwell, Lauren http://orcid.org/0000-0001-9991-0757
Chan, Kin
Aman, Ahmed http://orcid.org/0000-0002-0275-205X
Prakesch, Michael http://orcid.org/0000-0003-2960-6471
Poda, Gennady
Mader, Pavel
Wong, Cassandra
Maier, Stefan
Kitaygorodsky, Julia
Larsen, Brett
Colwill, Karen http://orcid.org/0000-0002-8979-1659
Yin, Zhe
Ceccarelli, Derek F. http://orcid.org/0000-0002-2674-9234
Batey, Robert A. http://orcid.org/0000-0001-8808-7646
Taipale, Mikko http://orcid.org/0000-0003-3811-1761
Kurinov, Igor
Uehling, David
Wrana, Jeff
Durocher, Daniel http://orcid.org/0000-0003-3863-8635
Gingras, Anne-Claude http://orcid.org/0000-0002-6090-4437
Al-Awar, Rima
Therrien, Marc http://orcid.org/0000-0003-2047-7650
Sicheri, Frank http://orcid.org/0000-0002-9824-2117
Funding for this research was provided by:
Gouvernement du Canada | Instituts de Recherche en Santé du Canada | CIHR Skin Research Training Centre (FRN 414829, FDN 143343, FDN 144301, FDN 388023)
Banting Research Foundation
Ontario Research Foundation (RE08-065, RE08-065, RE08-065, RE08-065)
U.S. Department of Health & Human Services | NIH | National Institute of General Medical Sciences (P41 GM103403)
NIH-ORIP HEI grant
Terry Fox Research Institute
Canada Research Chairs (Tier1, Tier1, Tier1)
Canadian Cancer Society Research Institute (CCSRI-Impact 706165, CCSRI-Impact 704116)
Article History
Received: 11 November 2019
Accepted: 1 July 2020
First Online: 10 August 2020
Competing interests
: F.S. and D.D. are founders and consultants for Repare Therapeutics. Host institutions LTRI and OICR have filed a patent relating to the PROTAC molecules presented in this study and their uses (pending USPA No. 62/812,567; applicants are G. Poda, G. Posternak and F.S.). No competing interests were disclosed by the other authors.