Lim, Kok Haw Jonathan https://orcid.org/0000-0002-6544-9218
Schulz, Oliver
Lobon, Irene https://orcid.org/0000-0003-1170-9915
Castro-Dopico, Tomas https://orcid.org/0000-0002-6964-5478
Zapata, Luis
Giampazolias, Evangelos
Frederico, Bruno
Castellanos, Carlos A. https://orcid.org/0000-0003-3615-2009
Buck, Michael D. https://orcid.org/0000-0002-9611-1199
Stainier, William https://orcid.org/0009-0003-6182-4003
Chakravarty, Probir
Kelly, Gavin https://orcid.org/0000-0001-7219-560X
Rogers, Neil C. https://orcid.org/0000-0001-8977-7585
Cardoso, Ana
Lee, Sonia
Vash, Brian
Maiocco, Stephanie
Mehta, Raj
Strid, Jessica
Turajlić, Samra
Reis e Sousa, Caetano https://orcid.org/0000-0001-7392-2119
Article History
Received: 20 August 2024
Accepted: 27 October 2025
First Online: 2 January 2026
Competing interests
: B.V. and S.M. are employees of Apple Tree Partners. R.M. is an employee of and owns stock options in Adendra Therapeutics, which partly funded this work. S.T. has received speaking fees from Roche, Astra Zeneca, Novartis and Ipsen. C.R.S. owns stock options and/or is a paid consultant for Adendra Therapeutics, Montis Biosciences and Bicycle Therapeutics. C.R.S. is a Visiting Professor at Imperial College London and King’s College London and holds an honorary professorship at University College London. The other authors declare no competing interests.