Bhamidipati, Kartik
McIntyre, Alexa B. R. https://orcid.org/0000-0001-6965-6292
Kazerounian, Shideh
Ce, Gao
Wong, Soon W. https://orcid.org/0000-0002-7994-1836
Tran, Miles
Prell, Sean A.
Lau, Rachel https://orcid.org/0000-0002-8330-8048
Khedgikar, Vikram
Altmann, Christopher
Small, Annabelle
Madhu, Roopa
Presti, Sonia R. https://orcid.org/0000-0001-9427-1757
Anufrieva, Ksenia S.
Blazar, Philip E.
Lange, Jeffrey K.
Seifert, Jennifer A.
,
Donlin, Laura T.
,
Donlin, Laura T.
Smith, Melanie H.
Thomas, Ranjeny
,
Zuscik, Michael J.
Clay, Michael R.
Clauw, Andrew D.
Griffith, Melissa
Geohring, Terrin
Carry, Patrick M.
Holers, V. Michael
Ackert-Bicknell, Cherl L.
Moon, Daniel
Hogan, Craig A.
Frank, Rachel M.
Dayton, Michael R.
Leversedge, Fraser J.
Seidl, Adam J.
Moreland, Larry W.
Croft, Adam P. https://orcid.org/0000-0002-9487-0511
Smith, Melanie H. https://orcid.org/0000-0003-2464-8429
Donlin, Laura T. https://orcid.org/0000-0002-1428-090X
Lewis, Myles J. https://orcid.org/0000-0001-9365-5345
Jonsson, Anna H. https://orcid.org/0000-0002-9558-2474
Pitzalis, Costantino https://orcid.org/0000-0003-1326-5051
Thomas, Ranjeny https://orcid.org/0000-0002-0518-8386
Gravallese, Ellen M.
Brenner, Michael B. https://orcid.org/0000-0001-6202-8445
Korsunsky, Ilya
Wechalekar, Mihir D. https://orcid.org/0000-0001-6668-9638
Wei, Kevin https://orcid.org/0000-0002-1821-167X
Funding for this research was provided by:
U.S. Department of Health & Human Services | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases (K08AR077037)
U.S. Department of Health & Human Services | NIH | National Institute of Arthritis and Musculoskeletal and Skin Diseases (T32AR007530-36)
Burroughs Wellcome Fund Career Awards for Medical Scientists
Article History
Received: 11 March 2025
Accepted: 2 December 2025
First Online: 15 January 2026
Competing interests
: M.D.W. has a collaborative research agreement with Janssen Pharmaceuticals USA, although unrelated to the paper. I.K. has paid consulting and advisory roles with Mestag Therapeutics, Merck Sharp & Dohme and the Lupus Research Alliance. J.K.L. is a paid consultant for Smith and Nephew, is on the scientific advisory board for OnPoint Knee and has received royalties from Cambridge Scholars Publishing for book editing. E.M.G. is an associate editor at New England Journal of Medicine , receives textbook royalties from Elsevier for Rheumatology and receives royalties from Wolters Kluwer for UptoDate contributions. M.B.B. is a consultant to GSK, Third Rock Ventures, 4FO Ventures and Moderna and a consultant to and founder of Mestag Therapeutics. K.W. has a sponsored-research agreement from Merck Pharmaceuticals and 10x Genomics, and served as a consultant for Mestag Therapeutics and Santa Ana Bio. The other authors declare no competing interests.