Bulten, Wouter http://orcid.org/0000-0002-6129-5039
Kartasalo, Kimmo http://orcid.org/0000-0002-9470-4783
Chen, Po-Hsuan Cameron http://orcid.org/0000-0002-0083-4991
Ström, Peter
Pinckaers, Hans
Nagpal, Kunal
Cai, Yuannan
Steiner, David F. http://orcid.org/0000-0003-1297-0023
van Boven, Hester
Vink, Robert
Hulsbergen-van de Kaa, Christina
van der Laak, Jeroen http://orcid.org/0000-0001-7982-0754
Amin, Mahul B. http://orcid.org/0000-0001-5943-3634
Evans, Andrew J.
van der Kwast, Theodorus http://orcid.org/0000-0001-8640-5786
Allan, Robert
Humphrey, Peter A.
Grönberg, Henrik http://orcid.org/0000-0002-1073-2753
Samaratunga, Hemamali
Delahunt, Brett
Tsuzuki, Toyonori http://orcid.org/0000-0002-4855-4366
Häkkinen, Tomi
Egevad, Lars
Demkin, Maggie
Dane, Sohier
Tan, Fraser
Valkonen, Masi
Corrado, Greg S.
Peng, Lily
Mermel, Craig H. http://orcid.org/0000-0002-0816-3395
Ruusuvuori, Pekka
Litjens, Geert http://orcid.org/0000-0003-1554-1291
Eklund, Martin http://orcid.org/0000-0001-5032-5266
,
Brilhante, Américo
Çakır, Aslı
Farré, Xavier
Geronatsiou, Katerina
Molinié, Vincent
Pereira, Guilherme
Roy, Paromita
Saile, Günter
Salles, Paulo G. O.
Schaafsma, Ewout
Tschui, Joëlle
Billoch-Lima, Jorge
Pereira, Emíio M.
Zhou, Ming
He, Shujun
Song, Sejun
Sun, Qing
Yoshihara, Hiroshi
Yamaguchi, Taiki
Ono, Kosaku
Shen, Tao
Ji, Jianyi
Roussel, Arnaud
Zhou, Kairong
Chai, Tianrui
Weng, Nina
Grechka, Dmitry
Shugaev, Maxim V.
Kiminya, Raphael
Kovalev, Vassili
Voynov, Dmitry
Malyshev, Valery
Lapo, Elizabeth
Campos, Manuel
Ota, Noriaki
Yamaoka, Shinsuke
Fujimoto, Yusuke
Yoshioka, Kentaro
Juvonen, Joni
Tukiainen, Mikko
Karlsson, Antti
Guo, Rui
Hsieh, Chia-Lun
Zubarev, Igor
Bukhar, Habib S. T.
Li, Wenyuan
Li, Jiayun
Speier, William
Arnold, Corey
Kim, Kyungdoc
Bae, Byeonguk
Kim, Yeong Won
Lee, Hong-Seok
Park, Jeonghyuk
Funding for this research was provided by:
KWF Kankerbestrijding (KUN 2015-7970, KUN 2015-7970, KUN 2015-7970)
Google LLC, Verily Life Sciences
Syöpäsäätiö
Academy of Finland
ERAPermed
Nederlandse Organisatie voor Wetenschappelijk Onderzoek (016.186.152)
Vetenskapsrådet
Cancerfonden
Åke Wiberg Stiftelse
EIT Health, Prostatacancerförbundet
Article History
Received: 5 March 2021
Accepted: 8 November 2021
First Online: 13 January 2022
Competing interests
: W.B. and H.P. report grants from the Dutch Cancer Society, during the conduct of the present study. J.v.d.L. reports consulting fees from Philips, ContextVision and AbbVie, and grants from Philips, ContextVision and Sectra, outside the submitted work. G.L. reports grants from the Dutch Cancer Society and the NWO, during the conduct of the present study, and grants from Philips Digital Pathology Solutions and personal fees from Novartis, outside the submitted work. M.E. reports grants from Swedish Research Council, Swedish Cancer Society, Swedish eScience Research Center, EIT Health, Karolinska Institutet, Åke Wiberg Foundation and Prostatacancerförbundet. P.Ruusuvuori reports grants from Academy of Finland, Cancer Foundation Finland and ERAPerMed. H.G. has five patents (WO2013EP7425920131120, WO2013EP74270 20131120, WO2018EP52473 20180201, WO2015SE50272 20150311 and WO2013SE50554 20130516) related to prostate cancer diagnostics pending, and has patent applications licensed to A3P Biomedical. M.E. has four patents (WO2013EP74259 20131120, WO2013EP74270 20131120, WO2018EP52473 20180201 and WO2013SE50554 20130516) related to prostate cancer diagnostics pending, and has patent applications licensed to A3P Biomedical. P.-H.C.C., K.N., Y.C., D.F.S., M.D., S.D., F.T., G.S.C., L.P. and C.H.M. are employees of Google LLC and own Alphabet stock, and report several patents granted or pending on machine-learning models for medical images. M.B.A. reported receiving personal fees from Google LLC during the conduct of the present study and receiving personal fees from Precipio Diagnostics, CellMax Life and IBEX outside the submitted work. A.E. is employed by Mackenzie Health, Toronto. T.v.d.K. is employed by University Health Network, Toronto; the time spent on the project was supported by a research agreement with financial support from Google LLC. R.A. and P.A.H. were compensated by Google LLC for their consultation and annotations as expert uropathologists. H.Y. reports nonfinancial support from Aillis Inc. during the conduction of the present study. W.L., J.L., W.S. and C.A. have a patent (US 62/852,625) pending. K.Kim, B.B., Y.W. K., H.-S.L. and J.P. are employees of VUNO Inc. M.B.A. reported receiving personal fees from Google LLC during the conduct of the present study and receiving personal fees from Precipio Diagnostics, CellMax Life and IBEX outside the submitted work. A.E. is employed by Mackenzie Health, Torontoa. T.v.d.K. is employed by University Health Network, Toronto; the time spent on the project was supported by a research agreement with financial support from Google LLC. M.Z., R.A. and P.A.H. were compensated by Google LLC for their consultation and annotations as expert uropathologists. All other authors declare no competing interests.