Sevigny, Jeffrey http://orcid.org/0000-0003-0974-6434
Uspenskaya, Olga
Heckman, Laura Dean
Wong, Li Chin
Hatch, Daniel A.
Tewari, Ambika http://orcid.org/0000-0002-8740-5080
Vandenberghe, Rik http://orcid.org/0000-0001-6237-2502
Irwin, David J.
Saracino, Dario
Le Ber, Isabelle
Ahmed, Rebekah
Rohrer, Jonathan D.
Boxer, Adam L. http://orcid.org/0000-0002-1215-5064
Boland, Sebastian http://orcid.org/0000-0002-6694-2039
Sheehan, Patricia
Brandes, Alissa
Burstein, Suzanne R.
Shykind, Benjamin M.
Kamalakaran, Sitharthan
Daniels, Carter W. http://orcid.org/0000-0002-9043-8000
David Litwack, E. http://orcid.org/0000-0001-7607-9155
Mahoney, Erin
Velaga, Jenny
McNamara, Ilan
Sondergaard, Patricia
Sajjad, Syed A.
Kobayashi, Yvonne M. http://orcid.org/0009-0009-2405-5747
Abeliovich, Asa
Hefti, Franz
Funding for this research was provided by:
Eli Lilly and Company (n/a, n/a, n/a, n/a, n/a, n/a, n/a, n/a, n/a, n/a, n/a, n/a, n/a, n/a, n/a, n/a, n/a, n/a, n/a, n/a, n/a, n/a, n/a)
Article History
Received: 3 July 2023
Accepted: 3 April 2024
First Online: 14 May 2024
Competing interests
: J.S., O.U., L.D.H., L.C.W., D.A.H., A.T., S.B., P. Sheehan, A.B., S.R.B., B.M.S., S.K., C.W.D., E.D.L., E.M., J.V., I.M., P. Sondergaard, S.A.S., Y.M.K., A.A. and F.H. have been or currently are employees of Prevail Therapeutics, a wholly owned subsidiary of Eli Lilly and Company. R.V. serves as principal investigator in clinical trial agreements by the University of Leuven with Alector, AviadoBio, Biogen, Denali Therapeutics, Eli Lilly, Johnson & Johnson, NovoNordisk, Prevail, Roche and UCB, and he has consultancy agreements with ACImmune and Novartis. D.J.I. serves as principal investigator in clinical trial agreements with Prevail Therapeutics, Transposon, Passage Bio, Alector and Denali Therapeutics. D.S. is a sub-investigator of the Prevail study reported in this publication. I.L.B. is the national coordinator of the Prevail study in France and is an investigator in another study on genetic frontotemporal dementia sponsored by Alector (AL001). R.A. received speaker fees from Biogen and serves on scientific advisory boards for Eli Lilly, Biogen, Roche and Eisai. J.D.R. has provided consultancy and served on the medical advisory board for Prevail. He has also provided consultancy and served on medical advisory boards for Novartis, Wave Life Sciences, Alector, Aviado Bio, Arkuda and Denali Therapeutics. A.L.B. has served as a paid consultant to Applied Genetic Technologies Corporation, Alector, Alzprotect, Amylyx, Arkuda, Arrowhead, Arvinas, Aviado, Boehringer Ingelheim, Denali Therapeutics, Eli Lilly, GlaxoSmithKline, Humana, Life Edit, Merck, Modalis, Oligomerix, Oscotec, Roche, Transposon and Wave Life Sciences. His institution received research support from Biogen and Eisai for serving as a site investigator for clinical trials as well as from Regeneron.