Butler, Paul Monroe https://orcid.org/0000-0001-6166-2612
Yang, Jenny https://orcid.org/0009-0001-9594-2724
Brown, Roland
Hobbs, Matt https://orcid.org/0000-0003-4220-4805
Becker, Andrew
Penalver-Andres, Joaquin https://orcid.org/0000-0001-8181-7538
Syz, Philippe
Muller, Sofia
Cosne, Gautier
Juraver, Adrien https://orcid.org/0009-0004-4251-9609
Song, Han Hee
Saha-Chaudhuri, Paramita https://orcid.org/0000-0003-1987-320X
Roggen, Daniel https://orcid.org/0000-0001-8033-6417
Scotland, Alf https://orcid.org/0000-0001-9590-8617
Silveira, Natalia
Demircioglu, Gizem
Gabelle, Audrey
Hughes, Richard https://orcid.org/0000-0001-5532-406X
Erkkinen, Michael G.
Langbaum, Jessica B.
Lingler, Jennifer H.
Price, Pamela
Quiroz, Yakeel T. https://orcid.org/0000-0001-9714-8244
Sha, Sharon J.
Sliwinski, Marty
Porsteinsson, Anton P. https://orcid.org/0000-0002-0166-1738
Au, Rhoda https://orcid.org/0000-0001-7742-4491
Bianchi, Matt T.
Lenyoun, Hanson
Pham, Hung
Patel, Mithun
Belachew, Shibeshih https://orcid.org/0000-0003-3976-1950
Article History
Received: 26 March 2024
Accepted: 17 December 2024
First Online: 4 March 2025
Competing interests
: The following authors are employed by Apple, Inc.: P.M.B., J.Y., M.H., P.S., S.M., H.H.S., N.S., M.T.B., H.L., H.P. and M.P. The following authors are employed by Biogen, Inc.: P.M.B., R.B., M.H., A.B., J.P.-A., G.C., A.J., P.S.-C., D.R., A.S., G.D., A.G., R.H., S.B. J.B.L. is a full-time employee of Banner Health. Banner Alzheimer’s Institute receives funding from Eli Lilly for its collaborative partnership on TRAILBLAZER-ALZ 3; she reports receiving grants from the NIA unrelated to this project. A.P.P. has received personal fees from Acadia Pharmaceuticals, Athira, BMS, Cognitive Research Corp, IQVIA, Lundbeck, Novartis, ONO Pharmaceuticals, Otsuka, WCG, WebMD and Xenon, and grants to institution from Athira, Biogen, Cassava, Eisai, Eli Lilly, Genentech/Roche, Vaccinex, NIA, NIMH and DOD; he is a member of the Scientific Advisory Board of Alzheon, Athira, and Cognition Therapeutics. Y.T.Q. serves as consultant for Biogen on other unrelated projects. R.A. serves as scientific advisor to Signant Health and NovoNordisk. M.G.E., J.B.L., J.H.L., P.P., Y.T.Q., S.J.S., M.S., A.P.P. and R.A. all served as consultants to Biogen, Inc. on this project as members of the Intuition Study Scientific Committee.