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Authors
Smit, Roelof A. J.
Wade, Kaitlin H.
Hui, Qin
Arias, Joshua D. https://orcid.org/0000-0001-6545-6656
Yin, Xianyong https://orcid.org/0000-0001-6454-2384
Christiansen, Malene R.
Yengo, Loic
Preuss, Michael H.
Nakabuye, Mariam
Rocheleau, Ghislain
Graham, Sarah E.
Buchanan, Victoria L.
Chittoor, Geetha
Graff, Marielisa
Guindo-Martínez, Marta
Lu, Yingchang
Marouli, Eirini
Sakaue, Saori
Spracklen, Cassandra N.
Vedantam, Sailaja
Wilson, Emma P.
Chen, Shyh-Huei
Ferreira, Teresa
Ji, Yingjie
Karaderi, Tugce
Lüll, Kreete
Machado, Moara
Malden, Deborah E.
Medina-Gomez, Carolina
Moore, Amy
Rüeger, Sina
Akiyama, Masato
Allison, Matthew A.
Alvarez, Marcus
Andersen, Mette K.
Appadurai, Vivek
Arbeeva, Liubov
Bartell, Eric
Bhaskar, Seema
Bielak, Lawrence F.
Bis, Joshua C.
Bollepalli, Sailalitha
Bork-Jensen, Jette
Bradfield, Jonathan P.
Bradford, Yuki
Brandl, Caroline
Braund, Peter S.
Brody, Jennifer A.
Broeckel, Ulrich
Burgdorf, Kristoffer S.
Cade, Brian E.
Cai, Qiuyin
Camarda, Silvia
Campbell, Archie
Cañadas-Garre, Marisa
Chai, Jin-Fang
Chesi, Alessandra
Choi, Seung Hoan
Christofidou, Paraskevi
Couture, Christian
Cuellar-Partida, Gabriel
Danning, Rebecca
Degenhardt, Frauke
Delgado, Graciela E.
Delitala, Alessandro
Demirkan, Ayşe
Deng, Xuan
Dietl, Alexander
Dimitriou, Maria
Dimitrov, Latchezar
Dorajoo, Rajkumar
Eichelmann, Fabian
Eliasen, Anders U.
Engmann, Jorgen E.
Erdos, Michael R.
Fairhurst-Hunter, Zammy
Farmaki, Aliki-Eleni
Faul, Jessica D.
Fernandez-Lopez, Juan-Carlos
Forer, Lukas
Frank, Mirjam
Freitag-Wolf, Sandra
Fritsche, Lars G.
Fuchsberger, Christian
Galesloot, Tessel E.
Gao, Yan
Geller, Frank
Giannakopoulou, Olga
Giulianini, Franco
Gjesing, Anette P.
Goel, Anuj
Gordon, Scott D.
Gorski, Mathias
Grove, Jakob
Guo, Xiuqing
Gustafsson, Stefan
Haessler, Jeffrey
Hansen, Thomas F.
Havulinna, Aki S.
Haworth, Simon J.
Heard-Costa, Nancy
Hemerich, Daiane
Highland, Heather M.
Hindy, George
Ho, Yuk-Lam
Hofer, Edith
Holliday, Elizabeth
Horn, Katrin
Hornsby, Whitney E.
Hottenga, Jouke-Jan
Huang, Hongyan
Huang, Jie
Huerta-Chagoya, Alicia
Huo, Shaofeng
Hwang, Mi Yeong
Hwu, Chii-Min
Iha, Hiroyuki
Ikeda, Daisuke D.
Isono, Masato
Jackson, Anne U.
Jansen, Iris E.
Jiang, Yunxuan
Johansson, Ingegerd
Jonsson, Anna
Jørgensen, Torben
Kalafati, Ioanna P.
Kanai, Masahiro
Kanoni, Stavroula
Kårhus, Line L.
Kasturiratne, Anuradhani
Katsuya, Tomohiro
Kawaguchi, Takahisa
Kember, Rachel L.
Kentistou, Katherine A.
Kim, Daeeun
Kim, Han-Na
Kim, Young Jin
Kleber, Marcus E.
Knol, Maria J.
Kurbasic, Azra
Lauzon, Marie
Le, Phuong
Lea, Rodney
Lee, Jong-Young
Lee, Wen-Jane
Leonard, Hampton L.
Li, Hengtong
Li, Shengchao A.
Li, Xiaohui
Li, Xiaoyin
Liang, Jingjing
Lin, Honghuang
Lin, Kuang
Liu, Jun
Liu, Xueping
Lo, Ken Sin
Long, Jirong
Lores-Motta, Laura
Luan, Jian’an
Lyssenko, Valeriya
Lyytikäinen, Leo-Pekka
Mahajan, Anubha
Malik, Md Zubbair
Mamakou, Vasiliki
Mangino, Massimo
Manichaikul, Ani
Marten, Jonathan
Mattheisen, Manuel
McDaid, Aaron F.
Mei, Quanshun
Meiselbach, Heike
Melendez, Tori L.
Milaneschi, Yuri
Miller, Jason E.
Millwood, Iona Y.
Mishra, Pashupati P.
Mitchell, Ruth E.
Møllehave, Line T.
Mononen, Nina
Mucha, Sören
Munz, Matthias
Mykkänen, Juha
Nakatochi, Masahiro
Nardone, Giuseppe Giovanni
Nelson, Christopher P.
Nethander, Maria
Nho, Chu Won
Nielsen, Aneta A.
Nolte, Ilja M.
Nongmaithem, Suraj S.
Noordam, Raymond
Ntalla, Ioanna
Nutile, Teresa
Pandit, Anita
Pauper, Marc
Petersen, Eva R. B.
Petersen, Liselotte V.
Piluso, Francesco
Polašek, Ozren
Poveda, Alaitz
Pyarajan, Saiju
Raffield, Laura M.
Rakugi, Hiromi
Ramirez, Julia
Rasheed, Asif
Raven, Dennis
Rayner, Nigel W.
Riveros, Carlos
Rohde, Rebecca
Ruggiero, Daniela
Ruotsalainen, Sanni E.
Ryan, Kathleen A.
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Saxena, Richa
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Shen, Botong
Shi, Jingchunzi
Shin, Jae Hun
Sidore, Carlo
Sidorenko, Julia
Sim, Xueling
Slieker, Roderick C.
Smith, Albert V.
Smith, Jennifer A.
Smyth, Laura J.
Southam, Lorraine
Steinthorsdottir, Valgerdur
Sun, Liang
Takeuchi, Fumihiko
Taylor, Kent D.
Tayo, Bamidele O.
Tcheandjieu, Catherine
Terzikhan, Natalie
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Teumer, Alexander
Theusch, Elizabeth
Thompson, Deborah J.
Thorleifsson, Gudmar
Timmers, Paul R. H. J.
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van der Most, Peter J.
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van Setten, Jessica
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Wheeler, William A.
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Xia, Rui
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Yao, Jie
Young, Hannah
Yousri, Noha A.
Yu, Lei
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Zhang, Weihua
Zhang, Xinyuan
Zhao, Jing-Hua
Zhao, Wei
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Zimmermann, Martina E.
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‘t Hart, Leen M.
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Böger, Carsten A.
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Ida Chen, Yii-Der
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de Geus, Eco J. C.
de Groot, Lisette C. P. G. M.
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de Kleijn, Dominique P. V.
de Silva, H. Janaka
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den Hollander, Anneke I.
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Isasi, Carmen R.
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Jin, Zi-Bing
Jöckel, Karl-Heinz
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Joshi, Peter K.
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Jukema, J. Wouter
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Kang, Kui Dong
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Kardia, Sharon L. R.
Karpe, Fredrik
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Khera, Amit V.
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Kiemeney, Lambertus A. L. M.
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Kooner, Jaspal S.
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London, Barry
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Palmer, Colin N. A.
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Penninx, Brenda W. J. H.
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Porteous, David J.
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Scott, Rodney J.
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Tabara, Yasuharu
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Article History
Received: 31 October 2024
Accepted: 6 June 2025
First Online: 21 July 2025
Competing interests
: The views expressed in this article are those of the author(s) and not necessarily those of the NHS, the NIHR or the Department of Health. M.I.McC. (since June 2019) and A.Mah (since January 2020) are employees of Genentech and holders of Roche stock. Yu.J., Ji.S. and Ad.A. are employed by and hold stock or stock options in 23andMe, Inc. S.W.v.d.L. has received Roche funding for unrelated work. M.J.Ca. is Chief Scientist for Genomics England, a UK Government company. P.S. has received research awards from Pfizer, Inc. D.H. is currently employed at Bristol Myers Squibb. G.C.-P. is an employee of 23andMe, Inc. Since completing the work contributed to this paper, D.J.T. has left the University of Cambridge and is now employed by Genomics plc. I.N. is an employee and stock owner of Gilead Sciences; this work was conducted before employment by Gilead Sciences. P.Ki. received research support for basic, translational and clinical research projects from the German Research Foundation (DFG), the European Union, the British Heart Foundation, the Leducq Foundation, the Else-Kröner-Fresenius Foundation, the Dutch Heart Foundation (DHF), the Accelerating Clinical Trials funding stream in Canada, the Medical Research Council (UK) and the German Center for Cardiovascular Research and from several drug and device companies active in atrial fibrillation and has received honoraria from several such companies in the past but not in the last 5 years. P.Ki. is listed as inventor on two issued patents held by the University of Hamburg (Atrial Fibrillation Therapy WO 2015140571 and Markers for Atrial Fibrillation WO 2016012783). M.R. received consultancy fees from Bayer (OCEANIC-AF national PI) and InCarda Therapeutics (RESTORE-SR national PI) to the institution, unrelated to this research/dataset. M.J.Cu. has served on advisory boards or consulted for Boston Scientific, Biosense Webster, Janssen Scientific Affairs and Johnson & Johnson. R.J.F.L. has acted as a member of advisory boards and as a speaker for Eli Lilly and the Novo Nordisk Foundation, for which she has received fees. S.N. is a scientific advisor to Circle software, ADAS software, CardioSolv and ImriCor and receives grant support from Biosense Webster, ADAS software and ImriCor. S.A.Lu. is an employee of Novartis. S.A.Lu. received sponsored research support from Bristol Myers Squibb, Pfizer, Boehringer Ingelheim, Fitbit, Medtronic, Premier and IBM and has consulted for Bristol Myers Squibb, Pfizer, Blackstone Life Sciences and Invitae. P.T.E. receives sponsored research support from Bayer AG, Bristol Myers Squibb, Pfizer and Novo Nordisk; he has also served on advisory boards or consulted for Bayer AG. Her.S. has received honoraria for consulting from AstraZeneca, MSD/Merck, Daiichi, Servier, Amgen and Takeda Pharma. He has additionally received honoraria for lectures and/or chairs from AstraZeneca, BayerVital, BRAHMS, Daiichi, Medtronic, Novartis, Sanofi and Servier. S.E.G. is employed by Regeneron. C.J.W. is employed by Regeneron. B.M.P. serves on the Steering Committee of the Yale Open Data Access Project funded by Johnson & Johnson. K.S. is employed by deCODE Genetics/Amgen, Inc. Va.S. is employed by deCODE Genetics/Amgen, Inc. G.T. is employed by deCODE Genetics/Amgen, Inc. U.T. is employed by deCODE Genetics/Amgen, Inc. E.Ba. is an employee of Empirico, Inc. Al.K. declares having received research grants through his affiliation from Novo Nordisk and Pharmaserve Lilly and consulting honoraria from Pharmaserve Lilly, Sanofi-Aventis, Novo Nordisk, MSD, AstraZeneca, ELPEN Pharma, Boehringer Ingelheim, Galenica Pharma, Epsilon Health and Winmedica. J.N.H. holds equity in Camp4 Therapeutics. A.E.L. is currently employed by and holds stock in Regeneron Pharmaceuticals, Inc. G.R.A. is an employee of Regeneron Pharmaceuticals and owns stock and stock options in Regeneron Pharmaceuticals. A.Pa. is currently employed by and holds stock in Regeneron Pharmaceuticals. O.G. is an employee and stock owner of UCB Pharma; this work was conducted before employment by UCB. N.G. is currently employed at Novo Nordisk A/S. M.E.K. is employed by SYNLAB Holding Deutschland GmbH. W.M. reports grants and personal fees from AMGEN, BASF, Sanofi, Siemens Diagnostics, Aegerion Pharmaceuticals, AstraZeneca, Danone Research, Numares, Pfizer and Hoffmann-La Roche; personal fees from MSD and Alexion; and grants from Abbott Diagnostics, all outside the submitted work. W.M. is employed by Synlab Holding Deutschland GmbH. C.J.O. is a current employee of Novartis Biomedical Research. S.M.D. receives research support from RenalytixAI and in-kind research support from Novo Nordisk, outside the scope of the current research. Ca.S. is currently employed by and holds stock in Regeneron Pharmaceuticals. J.C.F. received speaking honoraria from AstraZeneca, Merck and Novo Nordisk for talks over which he had full control of content and a consulting honorarium from AstraZeneca. H.L.L. receives support from a consulting contract between Data Tecnica International and the National Institute on Aging (NIA), National Institutes of Health (NIH). M.A.N. receives support from a consulting contract between Data Tecnica and the NIA, NIH. T.D.S. is a co-founder and shareholder of ZOE, Ltd. P.R.H.J.T. is a salaried employee of BioAge Labs, Inc. A.I.d.H. is currently an employee of AbbVie. The remaining authors declare no competing interests.
