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Authors
Farinas, Amelia https://orcid.org/0000-0002-6697-8883
Rutledge, Jarod
Bot, Veronica Augustina https://orcid.org/0009-0008-5060-1142
Western, Daniel https://orcid.org/0000-0003-3725-9553
Ying, Kejun
Lawrence, Kathryn A. https://orcid.org/0000-0002-7304-8318
Oh, Hamilton Se-Hwee https://orcid.org/0000-0001-8192-7593
Yoon, Seonghyun https://orcid.org/0009-0009-2780-7465
Ding, Daisy Yi
Tsai, Andy P. https://orcid.org/0000-0001-6400-544X
Moran-Losada, Patricia
Timsina, Jigyasha
Le Guen, Yann https://orcid.org/0000-0001-6649-8364
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Montgomery, Stephen B. https://orcid.org/0000-0002-5200-3903
Baker, David https://orcid.org/0000-0001-7896-6217
Poston, Kathleen L. https://orcid.org/0000-0003-3424-7143
Wagner, Anthony D. https://orcid.org/0000-0003-0624-4543
Mormino, Elizabeth
Cruchaga, Carlos https://orcid.org/0000-0002-0276-2899
Wyss-Coray, Tony https://orcid.org/0000-0001-5893-0831
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Funding
Funding for this research was provided by:
U.S. Department of Health & Human Services | NIH | National Institute on Aging (P50AG047366, P30AG066515, AG072255)
Alzheimer's Association (ADSF-25-1451396-C, ZEN-22-848604)
Additional funding from the Milky Way Research Foundation and the Knight Initiative for Brain Resilience
Foundation for the National Institutes of Health (T32MH020016, F99AG088431, T32HG000044, R01AG048076, R21AG058859, R01AG044546, P01AG003991, RF1AG053303, RF1AG058501, U01AG058922)
U.S. Department of Health & Human Services | NIH | National Institute of Neurological Disorders and Stroke (NS115114)
Michael J. Fox Foundation for Parkinson's Research
Stanford Wu Tsai Neurosciences Institute Stanford Center for Precision Health and Integrated Diagnostics
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Article History
Received: 21 April 2025
Accepted: 10 June 2025
First Online: 15 July 2025
Competing interests
: T.W.-C., J.R. and H.S.O. are co-founders and scientific advisors of Teal Omics Inc. and have received equity stakes. T.W.-C. is a co-founder and scientific advisor of Alkahest Inc. and Qinotto Inc. and has received equity stakes in these companies. C.C. has received research support from GSK and EISAI. C.C. is a member of the scientific advisory board of Circular Genomics and owns stock and a member of the Scientific Advisory Board of ADmit. K.L.P. is on the Scientific Advisory Board for Amprion and is a consultant for Novartis, Biohaven, Curasen and Neuron23, where she receives consulting fees. S.B.M. is an advisor to MyOme, PhiTech and Valinor Discovery. The remaining authors declare no competing interests.
