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Authors
Saito, Yuki https://orcid.org/0000-0003-2686-9604
Horie, Sara
Kogure, Yasunori https://orcid.org/0000-0003-1158-5131
Mizuno, Kota
Ito, Yuta
Mizukami, Yosuke
Kim, Haryoon
Tamura, Zen
Koya, Junji https://orcid.org/0000-0002-0605-1226
Funakoshi, Takeru
Hirata, Kenro https://orcid.org/0000-0003-4536-7781
Kataoka, Keisuke https://orcid.org/0000-0002-8263-9902
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Funding
Funding for this research was provided by:
Japan Agency for Medical Research and Development (JP22ama221510, JP25ama221543, and JP25gm1810002h0004)
MEXT | Japan Science and Technology Agency (JPMJMS2022)
Uehara Memorial Foundation (N/A)
MEXT | Japan Society for the Promotion of Science (JP 22K20808 and JP25K18889)
Kobayashi Foundation for Cancer Research (N/A)
Takeda Science Foundation (N/A)
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Article History
Received: 19 May 2025
Accepted: 29 October 2025
First Online: 6 January 2026
Competing interests
: Y.K. receives honoraria from Otsuka Pharmaceutical, outside the submitted work. T.F. receives clinical trial drugs free of charge from Chugai Pharmaceutical and MSD K.K., outside the submitted work. K.H. receives grants from MSD K.K., outside the submitted work. K. Kataoka receives grants and personal fees from Otsuka Pharmaceutical and Chugai Pharmaceutical, outside the submitted work. The other authors declare no competing interests.
