Rivard, Léna https://orcid.org/0000-0002-1340-0850
Khairy, Paul
Talajic, Mario
Tardif, Jean-Claude https://orcid.org/0000-0002-8200-8983
Healey, Jeffrey S.
Black, Sandra E. https://orcid.org/0000-0001-7093-8289
Andrade, Jason G. https://orcid.org/0000-0002-8493-5123
Field, Thalia S. https://orcid.org/0000-0002-1176-0633
Nault, Isabelle
Bherer, Louis
Massoud, Fadi
Nattel, Stanley https://orcid.org/0000-0002-5565-3311
Lanthier, Sylvain https://orcid.org/0000-0001-9762-5514
Racine, Normand
Roux, Jean-François https://orcid.org/0000-0001-7810-1678
Greiss, Isabelle https://orcid.org/0009-0009-0926-0494
Macle, Laurent
Guerra, Peter G.
Tadros, Rafik
Mayrand, Hélène
Gosselin, Gilbert
Conen, David
Bocti, Christian
Chayer, Céline
Deschaintre, Yan
Sandhu, Roopinder K.
Manlucu, Jaimie
Khaykin, Yaariv https://orcid.org/0000-0001-8649-0909
Verma, Atul
Mondésert, Blandine
Dyrda, Katia
Cadrin-Tourigny, Julia
Thibault, Bernard
Raymond-Paquin, Alexandre
Aguilar, Martin
Brouillette, Judith
Roussin, André
Robillard, Alain
Tremblay-Gravel, Maxime
David, Louis-Philippe
Cossette, Mariève
Parkash, Ratika
Guertin, Marie-Claude
Roy, Denis
,
Pandey, A. Shekhar
Pichette, Francis
Barrero, Miguel
Kus, Teresa
Lemieux, Ariane
Gaudreault, Valérie
Marzban, Peiman
Wong, Jorge
Sit, Peter Leong
Laflamme, David
Fowlis, Ronald
Quadros, Kenneth
Kapoor, Anmol
Jolly, Umjeet S.
Wilton, Stephen
Azzari, Fabian Alejandro
Dorian, Paul
Deslongchamps, François
Pesant, Yves
Vizel, Saul
Maung, TunZan
Heffernan, Michael
Nery, Pablo
Curnew, Greg
Bourgeois, Stéphanie
Essebag, Vidal
Kouz, Simon
Cormier, Luc
Vyselaar, John
Chehayeb, Raja
Khoo, Clarence
Gupta, Anil
Bessoudo, Ricardo
Bhargava, Rakesh
Sandrin, Franco
Schram, Gernot
St-Maurice, François
Tsui, Winston
Liang, William
Funding for this research was provided by:
Gouvernement du Canada | Instituts de Recherche en Santé du Canada | CIHR Skin Research Training Centre
Canadian Stroke Prevention Network (CSPIN); Montreal Heart Institute Foundation; BAYER Inc
Article History
Received: 1 April 2025
Accepted: 31 October 2025
First Online: 7 January 2026
Change Date: 4 February 2026
Change Type: Correction
Change Details: A Correction to this paper has been published:
Change Details: https://doi.org/10.1038/s41591-026-04245-5
Competing interests
: L.R. reports research grants from Canadian Stroke Prevention Intervention Network (CSPIN), Canadian Institutes of Health Research (CIHR), Montreal Heart Institute Foundation and salary support from the Fonds de recherche du Québec (FRQS); honoraria and consulting fees from Boston Scientific and honoraria from Biosense. J.-C.T. reports research grants from Boehringer-Ingelheim, Ceapro, DalCor Pharmaceuticals, Esperion, Merck, Novartis, Novo Nordisk, Pfizer and Verve; honoraria from DalCor Pharmaceuticals and Pfizer; minor equity interest from Dalcor Pharmaceuticals; authorship on a patent ‘use of colchicine after myocardial infarction’ assigned to the Montreal Heart Institute (J.-C.T. has waived his rights in the colchicine patents and does not stand to gain financially); and authorship on a patent ‘pharmacogenomics-guided CETP inhibition’. J.-S.H. reports support, grant, honoraria and consulting fees from Boston Scientific; grant and honoraria from BMS/Pfizer; grant from Medtronic; honoraria from Servier and Novartis; payment for expert testimony from Bayer. S.E.B. reports grants from Genentech, Optina, Roche, Eli Lilly, Eisa/Biogen Idec, Novo Nordisk, Lilly Avid, ICON, Aribio Co, Ontario Brain Institute, CIHR, Leducq Foundation, Heart and Stroke Foundation of Canada, NIH, Alzheimer’s Drug Discovery Foundation, Brain Canada, Weston Brain Institute, Canadian Partnership for Stroke Recovery, Canadian Foundation for Innovation, Focused Ultrasound Foundation, Alzheimer’s Association US, Queen’s University, Compute Canada Resources for Research Groups, CANARIE, Networks of Centres of Excellence of Canada; consulting fees from Roche, Biogen, Novo Nordisk, Eisai, Eli Lilly, DSR; honoraria from Biogen, Roche, Eisai and Cpdnetwork; participation on DSMB for Conference Board of Canada, World Dementia Council, University of Rochester and Ontario Dementia Care Alliance. J.G.A. reports honoraria from Abbott, Biosense-Webster Medtronic, Boston Scientific and Kardium. T.S.F. reports honoraria from Astrazeneca; payment for expert testimony from CMPA; participation on a DSMB for Novartis, Astrazeneca and Bayer; Board member for DESTINE Health and VGH/UBC Hospital Foundation. I.N. reports honoraria from Bayer, Servier, Medtronic and Biosense; support for travel from ERIM meeting 2024. F.M. reports consulting fees from Novo Nordisk and Eisai; honoraria from Pfizer. N.R. reports honoraria and participation on a DSMB from Clinical Event Committee. J.-F.R. reports consulting fees from Servier; honoraria from Bayer, BMS-Pfizer and Servier. R.T. reports grants and consulting fees from Bristol-Myers-Squibb Canada. G.G. reports grants from Novo Nordisk Canada Inc, Dalcor pharmaceutiques Canada Inc, Duke University, Merck Canada Inc, PPD Investigator Services, Novartis Canada, Montreal Heart Institute and Janssen Research & Development, LLC. D.C. received speaker fees from Servier, consulting fees from Trimedics and is supported by a PHRI career award. C.B. reports stock options from Imeka. Y.D. reports honoraria for presentation for Association des neurologues du Québec, Société de radiologie du Québec, Heart and Stroke Foundation of Canada and Centre de pédagogie appliquée aux sciences de la santé (Université de Montréal). R.K.S. reports grant NIH; consulting fees from Bayer. A.V. reports grants and consulting fees from Biosense, Medtronic, Abbott and medlumics; participation on a Data Safety Monitoring Board for Limit trial. J.C.-T. reports consulting fees from Bayer and BMS/Pfizer. J.B. reports consulting fees from Clinical Event Committee. M.A. reports consulting and speaker fees from Biosense-Webster and Abbott. R.P. reports research grants from Medtronic and Abbott; consulting fees from Medtronic and Biosense Webster. The other authors declare no competing interests.