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Authors
Yao, David https://orcid.org/0000-0002-2232-524X
Tycko, Josh https://orcid.org/0000-0002-4108-0575
Oh, Jin Woo https://orcid.org/0000-0002-3545-5481
Bounds, Lexi R. https://orcid.org/0000-0002-4734-3743
Gosai, Sager J.
Lataniotis, Lazaros https://orcid.org/0000-0001-6507-5191
Mackay-Smith, Ava https://orcid.org/0000-0003-0404-0563
Doughty, Benjamin R. https://orcid.org/0000-0003-0447-4468
Gabdank, Idan https://orcid.org/0000-0001-5025-5886
Schmidt, Henri
Guerrero-Altamirano, Tania
Siklenka, Keith
Guo, Katherine
White, Alexander D. https://orcid.org/0000-0002-5387-310X
Youngworth, Ingrid
Andreeva, Kalina
Ren, Xingjie https://orcid.org/0000-0002-2348-4162
Barrera, Alejandro https://orcid.org/0000-0001-9244-9822
Luo, Yunhai
Yardımcı, Galip Gürkan
Tewhey, Ryan https://orcid.org/0000-0002-4607-8001
Kundaje, Anshul https://orcid.org/0000-0003-3084-2287
Greenleaf, William J. https://orcid.org/0000-0003-1409-3095
Sabeti, Pardis C. https://orcid.org/0000-0002-9843-1890
Leslie, Christina https://orcid.org/0000-0002-4571-5910
Pritykin, Yuri https://orcid.org/0000-0001-6589-981X
Moore, Jill E.
Beer, Michael A. https://orcid.org/0000-0001-9955-3809
Gersbach, Charles A. https://orcid.org/0000-0003-1478-4013
Reddy, Timothy E. https://orcid.org/0000-0002-7629-061X
Shen, Yin https://orcid.org/0000-0001-9901-5613
Engreitz, Jesse M. https://orcid.org/0000-0002-5754-1719
Bassik, Michael C. https://orcid.org/0000-0001-5185-8427
Reilly, Steven K. https://orcid.org/0000-0003-3140-1483
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Funding
Funding for this research was provided by:
U.S. Department of Health & Human Services | NIH | National Human Genome Research Institute (UM1HG009435)
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Article History
Received: 2 December 2022
Accepted: 18 February 2024
First Online: 19 March 2024
Change Date: 22 March 2024
Change Type: Update
Change Details: In the version of the article initially published, in the caption to Fig. , the text now reading “Dots show an average over 100 bootstrap samples” originally read “...an average of over 100”. This has been amended in the HTML and PDF versions of the article.
Competing interests
: A.K. is a scientific cofounder of Ravel Biotechnology, is on the scientific advisory board of PatchBio, SerImmune, AINovo, TensorBio and OpenTargets, is a consultant with Illumina and owns shares in DeepGenomics, Immuni and Freenome. C.A.G. is a cofounder of Tune Therapeutics and Locus Biosciences and is an advisor to Tune Therapeutics and Sarepta Therapeutics. C.A.G. is an inventor on patents and patent applications related to CRISPR epigenome editing. J.T. and M.C.B. acknowledge an outside interest in Stylus Medicine. L.L. is currently employed by Sana Biotechnology. D.Y. is currently employed by Amber Bio. P.C.S. is a cofounder of and consultant to Sherlock Biosciences and board member of Danaher Corporation. P.C.S. is a shareholder in both companies. W.J.G. is a cofounder of Epinomics and an advisor to 10x Genomics, Guardant Health and Centrillion. J.M.E. is an inventor on patents and patent applications related to CRISPR screening technologies, received materials from 10x Genomics unrelated to this study, and received speaking honoraria from GSK plc. The remaining authors declare no competing interests.
