Ramezani, Meraj
Weisbart, Erin https://orcid.org/0000-0002-6437-2458
Bauman, Julia
Singh, Avtar
Yong, John https://orcid.org/0000-0002-4914-2259
Lozada, Maria
Way, Gregory P. https://orcid.org/0000-0002-0503-9348
Kavari, Sanam L.
Diaz, Celeste
Leardini, Eddy https://orcid.org/0009-0004-8090-0355
Jetley, Gunjan
Pagnotta, Jenlu https://orcid.org/0000-0001-5027-2256
Haghighi, Marzieh https://orcid.org/0000-0002-0867-8364
Batista, Thiago M.
Pérez-Schindler, Joaquín
Claussnitzer, Melina https://orcid.org/0000-0003-2450-736X
Singh, Shantanu https://orcid.org/0000-0003-3150-3025
Cimini, Beth A. https://orcid.org/0000-0001-9640-9318
Blainey, Paul C. https://orcid.org/0000-0002-4889-8783
Carpenter, Anne E. https://orcid.org/0000-0003-1555-8261
Jan, Calvin H.
Neal, James T. https://orcid.org/0000-0002-3962-8570
Funding for this research was provided by:
Novo Nordisk Fonden (NNF21SA0072102)
U.S. Department of Health & Human Services | NIH | National Institute of General Medical Sciences (1DP2GM146252)
Article History
Received: 6 August 2023
Accepted: 25 October 2024
First Online: 27 January 2025
Competing interests
: C.H.J. and J.Y. are employees of Calico Life Sciences LLC. S.S. and A.E.C. serve as scientific advisors for companies that use image-based profiling and Cell Painting (A.E.C: Recursion, SyzOnc and S.S.: Waypoint Bio, Dewpoint Therapeutics) and receive honoraria for occasional talks at pharmaceutical and biotechnology companies. P.C.B. is a consultant to or holds equity in 10X Genomics, General Automation Lab Technologies/Isolation Bio, Celsius Therapeutics, Next Gen Diagnostics, Cache DNA, Concerto Biosciences, Stately, Ramona Optics, Bifrost Biosystems and Amber Bio. The laboratory of P.C.B. also received research funding from Merck and Genentech for work related to genetic screening. The Broad Institute and MIT may seek to commercialize aspects of this work, and related applications for intellectual property have been filed, including WO2019222284A1 ‘In situ cell screening methods and systems’. The other authors declare no competing interests.