Kronenberg, Zev https://orcid.org/0000-0002-7627-9808
Nolan, Cillian
Porubsky, David https://orcid.org/0000-0001-8414-8966
Mokveld, Tom https://orcid.org/0000-0003-1905-5442
Rowell, William J. https://orcid.org/0000-0002-7422-1194
Lee, Sangjin
Dolzhenko, Egor
Chang, Pi-Chuan https://orcid.org/0000-0003-3021-6446
Holt, James M. https://orcid.org/0000-0001-6411-9236
Saunders, Christopher T. https://orcid.org/0000-0002-0726-7600
Olson, Nathan D. https://orcid.org/0000-0003-2585-3037
Steely, Cody J.
McGee, Sean
Guarracino, Andrea https://orcid.org/0000-0001-9744-131X
Koundinya, Nidhi https://orcid.org/0009-0008-7155-1287
Harvey, William T.
Watkins, W. Scott
Munson, Katherine M. https://orcid.org/0000-0001-8413-6498
Hoekzema, Kendra
Chua, Khi Pin
Chen, Xiao https://orcid.org/0000-0002-1432-268X
Fanslow, Cairbre
Lambert, Christine
Dashnow, Harriet https://orcid.org/0000-0001-8433-6270
Garrison, Erik https://orcid.org/0000-0003-3821-631X
Smith, Joshua D.
Lansdorp, Peter M. https://orcid.org/0000-0001-7435-1071
Zook, Justin M. https://orcid.org/0000-0003-2309-8402
Carroll, Andrew https://orcid.org/0000-0002-4824-6689
Jorde, Lynn B.
Neklason, Deborah W. https://orcid.org/0000-0002-4546-7080
Quinlan, Aaron R. https://orcid.org/0000-0003-1756-0859
Eichler, Evan E. https://orcid.org/0000-0002-8246-4014
Eberle, Michael A. https://orcid.org/0000-0001-8965-1253
Funding for this research was provided by:
United States Department of Commerce | National Institute of Standards and Technology (Intramural Funding, Intramural Funding)
U.S. Department of Health & Human Services | NIH | Center for Information Technology (R35GM118335, R01HG002385)
U.S. Department of Health & Human Services | NIH | National Human Genome Research Institute (R00HG011657)
Article History
Received: 2 October 2024
Accepted: 12 June 2025
First Online: 4 August 2025
Competing interests
: Z.K., C.N., T.M., W.J.R., S.L., E.D., J.M.H., C.T.S., K.P.C., C.F., C.L., X.C. and M.A.E. are employees and shareholders of PacBio. Z.K. holds private equity in Phase Genomics. P.-C.C. and A.C. are employees and shareholders of Google LLC. E.E.E. is a scientific advisory board (SAB) member of Variant Bio, Inc. All other authors have no competing interests.