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A perturbed gene network containing PI3K–AKT, RAS–ERK and WNT–β-catenin pathways in leukocytes is linked to ASD genetics and symptom severity

Published Online: 2019-09-23

Published Print: 2019-10

Authors

Gazestani, Vahid H.

Pramparo, Tiziano

Nalabolu, Srinivasa

Kellman, Benjamin P. https://orcid.org/0000-0002-0780-6096
Murray, Sarah

Lopez, Linda

Pierce, Karen

Courchesne, Eric https://orcid.org/0000-0002-3772-5799
Lewis, Nathan E. https://orcid.org/0000-0001-7700-3654
Funding

Funding for this research was provided by:

Brain and Behavior Research Foundation

U.S. Department of Health & Human Services | NIH | National Institute of Mental Health (R01-MH080134, R01-MH104446, R01-MH110558, P50-MH081755)

National Foundation for Autism Research
License Information

Text and Data Mining valid from 2019-09-23

Version of Record valid from 2019-09-23
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Article History

Received: 3 November 2018

Accepted: 7 August 2019

First Online: 23 September 2019

Competing interests

: V.H.G., T.P., E.C. and N.E.L. report serving as investigators on a patent pending assignment to University of California, San Diego about utilizing the developed framework in this work to discover biomarkers for the diagnosis and prognosis of complex diseases and disorders.

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