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Nasal anti-CD3 monoclonal antibody ameliorates traumatic brain injury, enhances microglial phagocytosis and reduces neuroinflammation via IL-10-dependent Treg–microglia crosstalk

Crossref DOI link: https://doi.org/10.1038/s41593-025-01877-7

Published Online: 2025-02-27

Published Print: 2025-03

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Izzy, Saef https://orcid.org/0000-0002-2822-6736
Yahya, Taha

Albastaki, Omar

Abou-El-Hassan, Hadi https://orcid.org/0000-0002-2765-291X
Aronchik, Michael

Cao, Tian

De Oliveira, Marilia Garcia

Lu, Kuan-Jung

Moreira, Thais G.

da Silva, Patrick

Boucher, Masen L. https://orcid.org/0000-0002-5972-4316
Beauchamp, Leah C.

S. LeServe, Danielle

Brandao, Wesley Nogueira

Carolina Durão, Ana

Lanser, Toby

Montini, Federico

Lee, Joon-Hyuk

Bernstock, Joshua D.

Kaul, Megha

Pasquarelli-do-Nascimento, Gabriel

Chopra, Kusha

Krishnan, Rajesh

Mannix, Rebekah

Rezende, Rafael M. https://orcid.org/0000-0003-3998-8012
Quintana, Francisco J. https://orcid.org/0000-0001-8156-0736
Butovsky, Oleg https://orcid.org/0000-0003-0186-8867
Weiner, Howard L. https://orcid.org/0000-0003-0203-9681
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Text and Data Mining valid from 2025-02-27

Version of Record valid from 2025-02-27
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Article History

Received: 17 October 2022

Accepted: 20 December 2024

First Online: 27 February 2025

Competing interests

: H.L.W. is on the scientific advisory board of Tiziana Life Sciences.

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