da Rocha, Joana F. https://orcid.org/0000-0002-2496-4061
Lance, Michelle L.
Luo, Renhao https://orcid.org/0000-0003-3489-1799
Schlachter, Pius https://orcid.org/0009-0009-3686-3952
Moreira, Luis
Iqbal, Mohamed Ariff https://orcid.org/0000-0002-5094-0717
Kuhn, Paula
Gardner, Robert S.
Valaris, Sophia
Islam, Mohammad R.
Gassner, Gabriele M. https://orcid.org/0009-0002-0386-5328
Mazuera, Sofia https://orcid.org/0009-0009-4430-6793
Healy, Kaela
Shastri, Sanjana https://orcid.org/0009-0004-8245-8249
Hibbert, Nathaniel B.
Moran-Figueroa, Kristen V.
Haley, Erin B.
Pfeiffer, Ryan D.
Aygar, Sema https://orcid.org/0000-0001-8112-0343
Kastanenka, Ksenia V.
Brase, Logan https://orcid.org/0000-0002-7175-3208
Harari, Oscar https://orcid.org/0000-0002-2635-6975
Benitez, Bruno A. https://orcid.org/0000-0002-2699-3878
Tucker, Nathan R.
Wrann, Christiane D. https://orcid.org/0000-0001-6066-8799
Funding for this research was provided by:
U.S. Department of Health & Human Services | NIH | National Institute of Neurological Disorders and Stroke (NS117694, NS118146, NS127211)
U.S. Department of Health & Human Services | NIH | National Institute on Aging (AG062904, AG064580, AG072054, AG066171, AG057777, AG072464)
Cure Alzheimer's Fund
SPARC Award from the McCance Center for Brain Health; Hassenfeld Clinical Scholar Award; Claflin Distinguished Scholar Award;
Archer Foundation
BIDMC 2023 Translational Research Hub Spark Grant Award
U.S. Department of Health & Human Services | NIH | National Heart, Lung, and Blood Institute (HL140187)
Article History
Received: 13 June 2023
Accepted: 3 April 2025
First Online: 12 June 2025
Competing interests
: C.D.W. is an academic co-founder and consultant for Aevum Therapeutics and has a financial interest in Aevum Therapeutics, a company developing drugs that harness the protective molecular mechanisms of exercise to treat neurodegenerative and neuromuscular disorders. Her interests were reviewed and are managed by the MGH and Mass General Brigham in accordance with their conflict-of-interest policies. The other authors declare no competing interests.