Aarrestad, Isak K.
Cameron, Lindsay P. https://orcid.org/0000-0002-8420-7898
Fenton, Ethan M.
Casey, Austen B. https://orcid.org/0000-0002-4670-851X
Rijsketic, Daniel R. https://orcid.org/0000-0002-2197-0730
Patel, Seona D.
Sambyal, Rohini
Johnson, Shane B. https://orcid.org/0000-0003-3425-9726
Ly, Calvin
Viswanathan, Jayashri
Barragan, Eden V.
Lozano, Stephanie A.
Seban, Nicolas
Hu, Hongru https://orcid.org/0000-0003-0497-4796
Powell, Noel A.
Chytil, Milan
Meyer, Retsina
Rose, David
Hempel, Chris
Olson, Eric
Hansen, Hanne D. https://orcid.org/0000-0001-5564-7627
Madsen, Clara A. https://orcid.org/0000-0002-3240-0223
Knudsen, Gitte M. https://orcid.org/0000-0003-1508-6866
Redd, Chase
Wheeler, Damian G.
Guanzon, Nathaniel
Muir, Jessie
Hennessey, Joseph J. https://orcid.org/0000-0003-0981-4695
Quon, Gerald https://orcid.org/0000-0002-1716-0153
McCorvy, John D. https://orcid.org/0000-0001-7555-9413
Gandhi, Sunil P.
Rasmussen, Kurt
Liston, Conor https://orcid.org/0000-0002-1639-5401
Gray, John A. https://orcid.org/0000-0002-7287-0748
Heifets, Boris D. https://orcid.org/0000-0003-1474-0379
Nord, Alex S. https://orcid.org/0000-0003-4259-7514
Kim, Christina K. https://orcid.org/0000-0002-1466-7098
Olson, David E. https://orcid.org/0000-0002-4517-0543
Funding for this research was provided by:
U.S. Department of Health & Human Services | National Institutes of Health (R01GM128997, R35GM148182, R01DA056365, T32MH112507, T32GM113770, T32GM099608, R44MH119989, R35GM133421, R01MH130591, P50DA042012, R35GM119831, DP2MH136588)
Camille and Henry Dreyfus Foundation
Hellman Foundation
Boone Family Foundation; WoodNext Foundation, Delix Therapeutics
UC | University of California, Davis (Human Genetics Focus Group grant, Human Genetics Focus Group grant, Davis Provost’s Undergraduate Fellowship, Human Genetics Focus Group grant)
Gouvernement du Canada | Instituts de Recherche en Santé du Canada | CIHR Skin Research Training Centre (202210MFE-491520-297096)
Boone Family Foundation
Article History
Received: 23 January 2025
Accepted: 12 June 2025
First Online: 4 August 2025
Competing interests
: D.E.O. is a cofounder of Delix Therapeutics, Inc., serves as the chief innovation officer and head of the scientific advisory board, and has had sponsored research agreements with Delix Therapeutics. Delix Therapeutics has licensed TBG-related technology from the University of California, Davis. C. Liston is a member of the scientific advisory board of Delix Therapeutics. The sponsors of this research were not involved in the conceptualization, design, decision to publish or preparation of the manuscript. However, several employees of Delix Therapeutics are coauthors of this article as they collected and analyzed data and approved the final version of the manuscript. Within the last 3 years, G.M.K. has been an advisor for Sanos, Onsero, Pangea Botanica, Gilgamesh and Seaport. At the time of manuscript submission, H.D.H. was employed by H. Lundbeck A/S. B.D.H. is on the scientific advisory board of Osmind and Journey Clinical and is a paid advisor to Arcadia Medicine, Inc. The other authors declare no competing interests.