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Article History

Received: 16 January 2019

Accepted: 5 September 2019

First Online: 2 October 2019

Competing Interests

: The authors declare no conflicts of interest. We wish to draw the attention of the Editor to the following facts which may be considered as apparent conflicts of interest and to significant financial contributions to this work. While a generous donation was used to set up the Zhendong Centre by Shanxi - Zhendong Pharmaceutical Co Ltd, they did not determine the research direction for this work, influence the analysis of the data or influence the writing of the paper. T.N.A: no competing interests, S.N. no competing interests, Z.Q. no competing interests, Y.H.L. no competing interests, J.C. no competing interests, H.Y.S. no competing interests, A.J.Y. no competing interests, T.P. no competing interests, H.D. no competing interests, R.D.K. no competing interests, W.W. is an employee of the Zhendong Research Institute seconded to Zhendong Centre to learn bioinformatics methods and provide technical advice regarding CKI., D.L.A. Director of the Zhendong Centre which was set up with a generous donation from the Zhendong Pharmaceutical Co Ltd. Zhendong Pharmaceutical has had no control over these experiments, their design or analysis and have not exercised any editorial control over the manuscript.