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Febuxostat, a Xanthine Oxidoreductase Inhibitor, Decreases NLRP3-dependent Inflammation in Macrophages by Activating the Purine Salvage Pathway and Restoring Cellular Bioenergetics

Crossref DOI link: https://doi.org/10.1038/s41598-019-53965-x

Published Online: 2019-11-21

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Nomura, Johji

Kobayashi, Tsunefumi

So, Alexander

Busso, Nathalie
Funding

Funding for this research was provided by:

FNS
License Information

Text and Data Mining valid from 2019-11-21

Version of Record valid from 2019-11-21
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Article History

Received: 21 November 2018

Accepted: 7 November 2019

First Online: 21 November 2019

Competing interests

: This work was supported by Teijin Pharma Limited. J.N. and T.K. are employees of Teijin Pharma Limited. N.B. and A.S. are funded by FNS (310030_153010).

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