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Computational modeling and synthesis of pyridine variants of benzoyl-phenoxy-acetamide with high glioblastoma cytotoxicity and brain tumor penetration

Crossref DOI link: https://doi.org/10.1038/s41598-023-39236-w

Published Online: 2023-07-28

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Ingraham, Charles H. IV

Stalinska, Joanna

Carson, Sean C.

Colley, Susan B.

Rak, Monika

Lassak, Adam

Peruzzi, Francesca

Reiss, Krzysztof

Jursic, Branko S.
Funding

Funding for this research was provided by:

National Institute of General Medical Sciences (P20 GM121288/6)

National Cancer Institute (1R41CA275433)

National Cancer Institute (1R41CA275433)
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Text and Data Mining valid from 2023-07-28

Version of Record valid from 2023-07-28
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Article History

Received: 3 April 2023

Accepted: 21 July 2023

First Online: 28 July 2023

Competing interests

: Dr. Branko Jursic is associated with Stepharm LLC, P.O. Box 24220, New Orleans, LA; Dr. Reiss is associated with WayPath Pharma LLC. 217 Sena Dr. Metairie LA 70005. Dr. Krzysztof Reiss and Dr. Branko Jursic have an LSU provisional patent for HR compounds presented in this manuscript (“Anticancer Composition and methods of use” 2932719-056-us2). Other authors do not have any competing interest in relation to this submission.

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