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Article History

Received: 20 December 2022

Accepted: 5 September 2023

First Online: 18 September 2023

Competing interests

: Johannes Breyer declares an advisory role for Pfizer; personal fees and travel costs from Apogepha, Ipsen, Janssen, Pfizer, and Photocure; research support from Cepheid and Janssen; and speakers honoraria from Ipsen, Pfizer, BMS, AstraZeneca, Merck, and Roche. Markus Eckstein declares advisory roles for Janssen, AstraZeneca, MSD, Cepheid, Diaceutics and GenomicHealth; personal fees and travel costs from Janssen, AstraZeneca, MSD, Cepheid, Diaceutics, GenomicHealth; research support from Janssen, AstraZeneca, Cepeheid and STRATIFYER; speakers honoraria from Janssen, AstraZeneca, MSD, Diaceutics, Roche, Astellas; part time employment at Diaceutics. Danijel Sikic declares no conflict of interest. Felix Wezel Advisory roles for Bayer, AstraZeneca; speaker honoraria and travel expenses from Medac; travel costs from Pfizer. Florian Roghmann declares speaker honoraria and travel expenses from Janssen, Roche, Merck, MSD, Pfizer, AstraZeneca, QED; advisory roles for Janssen, Roche, Merck, QED; research funding from Janssen. Mirco Brehmer declares no conflict of interest Ralph M. Wirtz is founder and employee of STRATIFYER Molecular Pathology GmbH. Jonas Jarczyk declares speakers honoraria form Medac GmbH. Philipp Erben declares research support from Janssen, Cepheid, and STRATIFYER. Veronika Bahlinger declares personal fees from MSD; research support from Gilead, speakers honoraria from MSD. Franziska Goldschmidt declares no conflict of interest Guido Fechner declares no conflict of interest Jack Chen is an employee of Cepheid. Ellen Paxinos is an employee of Cepheid. Michael Bates is an employee of Cepheid. Maximilian Haas declares speakers honoraria from Pfizer and Merck. Friedemann Zengerling declares honoraria from Astellas, Bayer Health, Bristol-Myers Squibb, Ipsen, Novartis, Roche, Sanofi/Aventis, Pfizer, Merck Healthcare; consulting fees from Apogepha, Bristol-Myers Squibb, Ipsen, Janssen-Cilag, Novartis, Roche, Sanofi/Aventis, Pfizer, Merck Healthcare, MSD; travel support from Bayer Health, Ipsen, Janssen-Cilag, Pfizer Christian Bolenz declares honoraria from AstraZeneca GmbH, Janssen-Cilag GmbH, Medac GmbH, Takeda Pharma GmbH, and Roche Pharma AG; and research support from AstraZeneca GmbH and ERBE Elektromedizin GmbH. Maximilian Burger declares honoraria from Bayer, BMS, Janssen, Medac, MSD, and Pfizer; consulting honoraria from Photocure. Arndt Hartmann declares honoraria from Agilent, AstraZeneca, BMS, CEA, Cepheid, Diaceutics, Ipsen, Janssen, Lilly, MSD, Phäon, QIAGEN, and Roche; consulting fees from Abbvie, Agilent, AstraZeneca, BMS, Cepheid, Diaceutics, Illumina, Ipsen, Janssen, Lilly, Nanostring, Phäon, and QIAGEN; travel support from Agilent, AstraZeneca, BMS, Cepheid, Diaceutics, Ipsen, Janssen, Lilly, MSD, Phäon, QIAGEN, and Roche; participation on data safety monitoring board or advisory board for Agilent, AstraZeneca, BMS, Cepheid, Diaceutics, Ipsen, Janssen, Lilly, MSD, Phäon, QIAGEN, and Roche; and has a leadership role as president of the German IAP. Maximilian Kriegmair declares an advisory role for BMS, Esai, Cepheid and Photocure; Speakers honoraria from, BMS, Pfizer, Merck, Astellas and Medac.