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Authors
Cecil, Raissa F.
Strohl, Lloyd
Thomas, Maddie K.
Schwartz, James L.
Timoshevskaya, Nataliya
Smith, Jeramiah J.
Voss, S. Randal
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Funding
Funding for this research was provided by:
Office of Research Infrastructure Programs (R24OD010435)
Office of Research Infrastructure Programs (R24OD010435)
Office of Research Infrastructure Programs (R24OD010435)
Office of Research Infrastructure Programs (R24OD010435)
Office of Research Infrastructure Programs (R24OD010435)
Office of Research Infrastructure Programs (R24OD010435)
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Article History
Received: 5 June 2024
Accepted: 16 September 2024
First Online: 27 September 2024
<!--Emphasis Type='Bold' removed-->Supplementary files
:
: The authors declare no competing interests.
: Manhattan plots showing the degree of association of segregating genotypes with <i>copper</i> phenotype vs. wildtype in BSR-Seq pools. (A) Values shown are -log10(p-values) from Fisher’s exact tests. (B) Values are Z-scores from statistical tests of allele frequency difference.
: Nucleotide sequence for wildtype <i>Tyrp1</i> showing where a nucleotide deletion (nonsense mutation at 1156 bp) occurs in the <i>copper Tyrp1</i> allele.
: Predicted amino acid sequence for wildtype Tyrp1 showing where the <i>copper</i> amino acid sequence is altered by a nonsense mutation that results in a stop codon at amino acid residue 415.
