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Human prolyl hydroxylase domain 2 reacts with O2 and 2-oxoglutarate to enable formation of inactive Fe(III).2OG.hypoxia-inducible-factor α complexes

Published Online: 2024-10-30

Authors

Fiorini, Giorgia

Marshall, Stephen A.

Figg, William D. Jr.

Myers, William K.

Brewitz, Lennart

Schofield, Christopher J.
Funding

Funding for this research was provided by:

Biotechnology and Biological Sciences Research Council (BB/L000121/1, BB/J001694/2, BB/R013829/1)

Cancer Research UK (C8717/A18245)

Wellcome Trust (091857/7/10/7)

Newton Abraham Scholarship

EPSRC (EP/L011972/1)
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Text and Data Mining valid from 2024-10-30

Version of Record valid from 2024-10-30
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Article History

Received: 16 July 2024

Accepted: 8 October 2024

First Online: 30 October 2024

Competing interests

: The authors declare no competing interests.

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