Ge, Alex Y.
Arab, Abolfazl
Dai, Raymond
Navickas, Albertas
Fish, Lisa
Garcia, Kristle
Asgharian, Hosseinali
Goudreau, Jackson
Lee, Sean
Keenan, Kathryn
Pappalardi, Melissa B.
McCabe, Michael T.
Przybyla, Laralynne
Goodarzi, Hani
Gilbert, Luke A.
Article History
Received: 6 December 2023
Accepted: 21 October 2024
First Online: 29 October 2024
Change Date: 5 December 2024
Change Type: Update
Change Details: The original online version of this Article was revised: In the original version of this Article, the text for the abstract of this article was incorrectly included as a “Summary” section after the Methods rather than as an "Abstract" at the start of the Article. The original Article has been corrected.
Competing interests
: A.Y.G., A.A., R.D., A.N., L.F., K.G., H.A., J.G., S.L., L.P. and H.G. declare no competing interests. K.K., M.B.P. and M.T.M. are employees and shareholders of GSK. L.A.G. has filed patents on CRISPR functional genomics and is a co-founder of Chroma Medicine.
: Subfigures and plots were generated using GraphPad Prism (GraphPad Software, La Jolla, CA), Python Matplotlib and R ggplot2. Cartoons of the dCas9 protein and sgRNA were adapted from images by the Innovative Genomics Institute, UC Berkeley and UCSF. All figures were assembled in Adobe Illustrator (Adobe, Inc.).