Fu, Zixuan
Xu, Xiaofang
Cao, Li
Xiang, Qianying
Gao, Qian
Duan, Huirong
Wang, Shuhan
Zhou, Liye
Yang, Xiujuan
Funding for this research was provided by:
National Natural Science Foundation of China (32301421, 32301421, 32301421, 32301421, 82204163, 32301421, 32301421, 32301421)
the Applied Basic Research Project of Shanxi Province, China (202203021221189)
Scientific and Technological Innovation Programs of Higher Education Institutions in Shanxi (2021L222)
Teaching Reform Innovation Programs of Higher Education Institutions in Shanxi (J20220435)
Article History
Received: 23 June 2024
Accepted: 12 November 2024
First Online: 19 November 2024
Declarations
:
: The NHANES database is publicly available and has been approved by the Institutional Review Board of the National Center for Health Statistics (NCHS). All participants provided written informed consent during their participation in the national survey conducted in the United States. Ethical review and approval were waived for this study as it involved secondary analysis and did not necessitate additional institutional review board approval.
: Not applicable.
: The authors declare no competing interests.
: Pb, Cd, Hg, Se, Cu, and Zn were significantly associated with cognitive function.An interaction between Cd and the other heavy metals (excepted for Pb).Exposure to the 6 heavy metals combined showed a positive linear association with IRT, DRT and a negative linear association with DSST.