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Authors
Ma, Huan
Ye, Tianzhen
Qu, Guofeng
Qin, Yilin
Liao, Jiali
Yang, Yuanyou
Zhang, Wei
Liu, Ning
Li, Feize
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Funding
Funding for this research was provided by:
Youth Talent Fund of Sichuan Academy of Medical Sciences and Sichuan Provincial People’s Hospital (2022QN32)
Fundamental Research Funds for the Central Universities
National Natural Science Foundation of China (12475349)
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Article History
Received: 28 February 2025
Accepted: 20 May 2025
First Online: 25 May 2025
Declarations
:
: The authors declare no competing interests.
: The authors declare that they have no conflict of interest.
: All animal studies were conducted in accordance with ARRIVE guidelines and approved by the Animal Welfare and Ethics Committee of Sichuan University. This article does not contain any studies with human participants performed by any of the authors.
: Cell viability of U87MG after incubated with different doses of PDA-FAPI, Representative immunofluorescent microscopy images of γ-H2AX foci in U87MG cells untreated or treated with different doses of astatine-211 for 3 h, Representative flow cytometric analysis of apoptosis in U87MG cells treated with different doses of astatine-211 and body weight changes in three groups (saline, astatine-211 and [211At]At-PDA-FAPI) during the therapeutic period.
