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Article History

Received: 16 January 2025

Accepted: 9 June 2025

First Online: 2 July 2025

Declarations

:

: The following authors Lara Perryman, Alison Findlay, Jonathan Foot, Amar Joshi, Amna Zahoor, Craig Turner, Dieter Hamprecht, Jana Baskar, Jessica Stolp, Ross Hamilton, Wenbin Zhou, Brett Carlton and Wolfgang Jarolimek have been employees of Syntara (the company that owns SNT-5382) or its predecessor, Pharmaxis, and the staff have stocks in the company. The remaining authors have no competing interests to declare. All authors have read and approved the manuscript.

: The study conformed to the principles of the Helsinki Declaration. All of the subjects provided written consent to participate in the study, and the Universidad the Navarra committee approved the study protocol.

: We confirm that all authors have read and approved this manuscript for submission. Furthermore, we affirm that the content of this manuscript has not been published or submitted for publication elsewhere.

: All animal procedures were approved by the Institutional Animal care and Use committee and conformed to the guide for the care and use of Laboratory Animals published by the U.S. National Institutes of Health (NIH Publication No. 85–23, revised in 1996).