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Authors
Hobbs, F. D. Richard
Dorward, Jienchi
Hayward, Gail
Yu, Ly-Mee
Saville, Benjamin R.
Butler, Christopher C.
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Hobbs, F. D. Richard
Dorward, Jienchi
Hayward, Gail
Yu, Ly-Mee
Saville, Benjamin R.
Butler, Christopher C.
Robinson, Jared
Bell, Charlotte Latimer
Gbinigie, Oghenekome
Van Hecke, Oliver
Ogburn, Emma
Thomas, Nicholas P. B.
Evans, Philip H.
Andersson, Monique
Bongard, Emily
Borek, Aleksandra
Grabey, Jenna
Harris, Victoria
Koshkouei, Mona
Patel, Mahendra G.
Berry, Nick
Detry, Michelle A.
Saunders, Christina T.
Fitzgerald, Mark
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Funding
Funding for this research was provided by:
UK Research and Innovation (CV220-074, CV220-074, CV220-074, CV220-074, CV220-074, CV220-074)
National Institute for Health and Care Research (MC_PC_19079, MC_PC_19079, MC_PC_19079, MC_PC_19079, MC_PC_19079, MC_PC_19079)
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Article History
Received: 6 December 2024
Accepted: 26 June 2025
First Online: 4 July 2025
Declarations
:
: The authors declare no competing interests.
: REC number: 20/SC/0158.
: 2020-001209-22 26/3/2020.
: ISRCTN86534580.
: 281958.
: CCB and FDRH were co-principal investigators of the trial, obtained funding, had full access to all the data in the study, take responsibility for the integrity of the data and the accuracy of the data analysis. FDRH and CCB decided to publish the paper. BS, L-MY, GH, JD, BS provided input on the trial design. L-MY and EO were responsible for acquisition, analysis, and interpretation of data. CCB, FDRH, L-MY, BS, JD drafted the manuscript. All authors critically revised the manuscript. BS, NB, L-MY, MAD, MF, CS, VH contributed to statistical analysis.
: Carol Green, Phil Hannaford, Paul Little (Chair), Tim Mustill, Matthew Sydes.
: Deborah Ashby (Chair), Nick Francis, Simon Gates, Gordon Taylor, Patrick White.
