Spiteri, Alanna G.
Steele, Joel R.
Lee, Han-Chung
Zhang, Haijian
Sun, Jiaqi
Schittenhelm, Ralf B.
Yu, Chien-Hsiung
McLean, Catriona
Masters, Colin L.
Goudey, Benjamin
Jin, Liang
Pan, Yijun
Funding for this research was provided by:
National Health and Medical Research Council (GNT2007912)
NHMRC-AMED 2022 Dementia Collaborative Research (GNT2022203)
Alzheimer’s Association grant (AARF1020292)
Article History
Received: 21 March 2025
Accepted: 10 July 2025
First Online: 30 September 2025
Declarations
:
: The authors declare no competing interests.
: All methods were carried out in accordance with relevant guidelines and regulations, separately for animal and human studies. All animal experiments are reported in accordance with the ARRIVE guidelines and were approved by the Florey Institute of Neuroscience and Mental Health Animal Ethics Committee (protocol number: 23–011-FINMH). The study was conducted in compliance with the Australian National Health and Medical Research Council Code of Practice. The use of postmortem human tissue was approved by The University of Melbourne Human Research Ethics Committee and Victorian Brain Bank. Informed consent was obtained from all donors, or next of kin prior to collection of tissue.